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Table 1 Data on body weight, food intake, fasting blood glucose, and blood lipid profile in both groups

From: The DPP-4 inhibitor sitagliptin attenuates the progress of atherosclerosis in apolipoprotein-E-knockout mice via AMPK- and MAPK-dependent mechanisms

 

Control

Sitagliptin

p value

Daily food intake (g/w)

37.13 ± 3.24

37.41 ± 3.57

0.82 (NS)

Body weight pretreatment (g)

18.01 ± 1.04

17.91 ± 0.71

0.79 (NS)

Body weight (g)

32.73 ± 1.43

32.1 ± 1.32

0.28 (NS)

Fasting blood glucose (mg/dl)

109.58 ± 10.65

111.09 ± 8.30

0.76 (NS)

Total cholesterol (mg/dl)

1211.02 ± 163.79

1260.41 ± 160.12

0.55 (NS)

Triglycerides (mg/dl)

60.73 ± 15.62

58.19 ± 12.94

0.73 (NS)

HDL cholesterol (mg/dl)

52.78 ± 5.25

97.76 ± 8.56

<0.001

LDL cholesterol (mg/dl)

919.61 ± 96.49

1030.10 ± 128.70

0.07 (NS)

VLDL cholesterol (mg/dl)

789.24 ± 157.62

821.99 ± 59.54

0.60 (NS)

  1. HDL: high-density lipoprotein; LDL: low-density lipoprotein; TG: triglyceride; VLDL: very low-density lipoprotein. Values are expressed as mean ± SD, n = 8–12 per group.