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Figure 3 | Cardiovascular Diabetology

Figure 3

From: The DPP-4 inhibitor sitagliptin attenuates the progress of atherosclerosis in apolipoprotein-E-knockout mice via AMPK- and MAPK-dependent mechanisms

Figure 3

Effects of sitagliptin on collagen fibers, macrophages, and smooth muscle cells in atherosclerotic lesions. Cross-sections of the aortic root were cut into slices and stained with Masson (A), anti-smooth muscle cell (B), and anti-macrophage antibody (C). The ratios occupied by collagen fibers (D), smooth muscle cells (E), and macrophages (F) in the aortic plaque were also evaluated. Values are mean ± SD; n = 6 per group; *p < 0.05.

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