Figure 3

Quantification of the protein levels of myosin light chain 2 (MLC2) in 60-week old liver-specific gck knockout mice. Representative Western blot images (A) and quantification of the MLC2 Western blots in heart homogenates (B) are shown for wild-type (gck^w/w) and gck knockout (gck^w/–) mice as well as knockout mice treated with insulin or rosiglitazone for 4 weeks. n = 3 for all samples. Asterisk (*) refers to statistical significance (P < 0.05) in comparisons with gck^w/– mice, while # refers to comparisons with gck^w/w mice.