Table 1 Characteristics of control subjects, overweight or obese patients and diabetic patients
Control group | Overweight or obese patients | Diabetic patients | p | |
|---|---|---|---|---|
n = 25 | n = 30 | n = 118 | ||
Age, years | 23 (22;25) | 37 (31;49)* | 61 (56;67)*† | <0.01 |
Gender (male/female) | 15/10 | 3/27* | 72/46† | <0.01 |
Body mass index, kg/m2 | 21.7 (20.4;23.0) | 34.1 (31.3;37.1)* | 30.0 (26.9;34.7)*† | <0.01 |
Hypertension (%) | NA | 7 (23.3) | 103 (87.3) | <0.01 |
Dyslipidemia (%) | NA | 12 (40.0) | 103 (87.3) | <0.01 |
Total cholesterol, mmol/l | 4.7 (4.4;5.5) | 4.4 (3.8;5.2) | 0.05 | |
HDL cholesterol, mmol/l | 1.21 (1.03;1.35) | 1.08 (0.92;1.3) | 0.06 | |
LDL cholesterol, mmol/l | 3.17 ± 0.90 | 2.65 ± 0.92 | <0.01 | |
Triglycerides, mmol/l | 1.17 (0.90;1.79) | 1.52 (1.10;2.20) | <0.05 | |
Smoking (%) | NA | 3 (10.0) | 23 (19.5) | NS |
FMD, % | 3.95 (1.43;5.25) | 4.25 (1.74;5.56) | 0.61 (-1.22;3.2)*† | <0.01§ |
Paradoxical vasoconstriction (%) | 3 (12) | 3 (10.0) | 47 (39.8)*† | <0.01§ |
VCAM, ng/ml | 485 (435;656) | 562 (430;677) | NS |