Low serum docosahexaenoic acid is associated with progression of coronary atherosclerosis in statin-treated patients with diabetes mellitus: results of the treatment with statin on atheroma regression evaluated by intravascular ultrasound with virtual histology (TRUTH) study

Table 3 Parameters evaluated by using grayscale and virtual histology intravascular ultrasound

	At baseline			At 8-month follow-up
	Progressors (n=26)	Regressors (n=24)	p value	Progressors (n=26)	Regressors (n=24)	p value
EEM volume index (mm³/mm)	16.97 ± 5.65	16.47 ± 6.17	0.77	17.01 ± 5.80	16.03 ± 6.04***	0.56
% change				0.2 ± 4.5	-2.7 ± 3.0	0.01
Plaque volume index (mm³/mm)	9.59 ± 3.84	9.48 ± 4.06	0.93	10.11 ± 3.86****	8.83 ± 3.61***	0.23
% change				6.3 ± 5.9	-6.4 ± 4.5	0.0001
Lumen volume index (mm³/mm)	7.38 ± 2.82	6.99 ± 2.37	0.6	6.89 ± 2.69**	7.20 ± 2.73	0.69
% change				-6.6 ± 9.0	2.4 ± 6.8	0.0002
Percent atheroma volume (%)	56.2 ± 8.6	57.0 ± 6.1	0.69	59.3 ± 7.8****	54.9 ± 6.4***	0.03
Nominal change (%)				3.2 ± 2.8	-2.2 ± 2.4	0.0001
Fibrous volume index (mm³/mm)	3.52 ± 2.29	3.72 ± 2.18	0.75	3.92 ± 1.98*	3.11 ± 1.80****	0.14
Change (mm³/mm)				0.40 ± 0.85	-0.61 ± 0.53	0.0001
Fibrofatty volume index (mm³/mm)	1.08 ± 0.77	1.42 ± 1.44	0.29	0.93 ± 0.84	1.06 ± 0.93	0.62
Change (mm³/mm)				-0.15 ± 0.57	-0.37 ± 0.94	0.31
Necrotic core volume index (mm³/mm)	1.01 ± 0.73	0.54 ± 0.30	0.005	1.10 ± 0.69	0.74 ± 0.49*	0.04
Change (mm³/mm)				0.09 ± 0.64	0.20 ± 0.38	0.47
Dense calcium volume index (mm³/mm)	0.64 ± 0.60	0.34 ± 0.18	0.02	0.75 ± 0.61	0.48 ± 0.43	0.08
Change (mm³/mm)				0.11 ± 0.34	0.13 ± 0.35	0.77
Average length (mm)	27.5 ± 16.3	26.1 ± 13.0	0.74	27.6 ± 17.8	26.3 ± 12.7	0.77

Data are expressed as mean ± SD. *p 〈 0.05, **p 〈 0.01, ***p 〈 0.001, ****p 〈 0.0001 compared with value at baseline.
EEM, external elastic membrane.

ISSN: 1475-2840