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Table 3 Effect of CAPA on the coronary arterial flow rate and heart rate

From: Caffeic acid phenethyl amide improves glucose homeostasis and attenuates the progression of vascular dysfunction in Streptozotocin-induced diabetic rats

CAPA (μM)

Normal rat hearts

Type 1 diabetic rat hearts

 

Coronary arterial flow rate (mL/min)

Heart rate (BPM)

n

Coronary arterial flow rate (mL/min)

Heart rate (BPM)

n

0

11.8 ± 1.0

236.1 ± 7.1

5

10.3 ± 0.6

207.8 ± 12.9

9

1

15.6 ± 1.2 *

234.2 ± 11.7

5

11.9 ± 0.9 *

208.5 ± 11.1

9

3

17.4 ± 1.3 *

234.1 ± 6.5

5

13.3 ± 1.1 *

203.2 ± 9.2

8

10

19.5 ± 0.7 *

218.0 ± 5.5

4

14.8 ± 1.4 *

205.5 ± 10.2

6

  1. Effect of CAPA on the coronary arterial flow rate (mL/min) and heart rate (BPM: beats per minute) in normal and type 1 diabetic rat hearts. Coronary arterial flow rate was measured after 30 min of equilibrium with retrograde perfusion at a constant pressure of 80 mmHg. Data (mean ± SEM) were obtained from 4–9 animals. * P < 0.05 compared with CAPA (0 μM)-administered animals.
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Cardiovascular Diabetology

ISSN: 1475-2840