Table 4 Independent correlates of any CVD event(s)
Variables | Any CVD event | ||
|---|---|---|---|
OR | 95%CI | P | |
Age, x year | 1.018 | 1.011-1.024 | <0.0001 |
Diabetes duration, x year | 1.019 | 1.013-1.025 | <0.0001 |
Gender, male | 1.746 | 1.550-1.967 | <0.0001 |
BMI, x unit | - | - | - |
Smoking | <0.0001 | ||
No | 1.0 | ||
Former | 1.413 | 1.254-1.591 | <0.0001 |
Current | 1.156 | 0.986-1.354 | 0.074 |
Triglycerides, x 0.0113 mmol/l | 0.999 | 0.999-1.000 | 0.040 |
HDL cholesterol, x 0.259 mmol/l | 0.983 | 0.978-0.987 | <0.0001 |
Dyslipidemia | 1.713 | 1.470-1.997 | <0.0001 |
Hypertension | 2.054 | 1.699-2.484 | <0.0001 |
Diabetes treatment, n (%) | <0.0001 | ||
Diet | 1.0 | ||
OHA | 1.266 | 1.038-1.544 | 0.020 |
Insulin + OHA | 1.228 | 0.942-1.601 | 0.128 |
Insulin | 2.051 | 1.623-2.593 | <0.0001 |
Albuminuria | 0.052 | ||
Normoalbuminuria | 1.0 | ||
Microalbuminuria | 1.167 | 1.030-1.323 | 0.015 |
Macroalbuminuria | 1.069 | 0.845-1.351 | 0.580 |
eGFR (MDRD) | <0.0001 | ||
≥90 ml/min/1.73 m2 | 1.0 | ||
60–89 ml/min/1.73 m2 | 1.116 | 0.975-1.278 | 0.112 |
30–59 ml/min/1.73 m2 | 1.820 | 1.531-2.162 | <0.0001 |
<30 ml/min/1.73 m2 | 2.278 | 1.541-3.367 | <0.0001 |
Retinopathy | <0.0001 | ||
No retinopathy | 1.0 | ||
Non advanced retinopathy | 1.295 | 1.122-1.495 | 0.0001 |
Advanced retinopathy | 1.298 | 1.084-1.554 | 0.005 |
MODEL 1 | |||
HbA 1c -MEAN, 1% increment | 1.062 | 1.011-1.114 | 0.016 |
MODEL 2 | |||
HbA 1c -MEAN, 1% increment | 1.062 | 1.011-1.114 | 0.016 |
HbA 1c -SD, 1% increment | - | - | - |
MODEL 3 | |||
HbA 1c -MEAN | 0.001 | ||
quartile 1 | 1.0 | ||
quartile 2 | 0.923 | 0.787-1.082 | 0.322 |
quartile 3 | 1.248 | 1.066-1.462 | 0.006 |
quartile 4 | 1.096 | 0.928-1.295 | 0.281 |
HbA 1c -SD quartiles | – | – | – |