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Table 3 HbA 1c -values and measures of HbA 1c -variability

From: Hemoglobin A1c variability as an independent correlate of cardiovascular disease in patients with type 2 diabetes: a cross-sectional analysis of the Renal Insufficiency and Cardiovascular Events (RIACE) Italian Multicenter Study

Variable n (%) Current HbA1c, % HbA1c-MEAN, % HbA1c-SD, % HbA1c-CV, % Adj-HbA1c-SD, %
No CVD 6,157 (74.3) 7.57±1.36 7.63±1.19 0.59±0.48 7.57±5.52 0.52±0.42
7.42 (6.70-8.28) 7.49 (6.81-8.31) 0.46 (0.28-0.73) 6.06 (3.94-9.37) 0.40 (0.26-0.67)
Any coronary event 1,373 (16.6) 7.85±1.34 7.88±1.20 0.60±0.45 7.40±5.13 0.53±0.39
7.70 (6.92-8.57) 7.77 (7.02-8.59) 0.47 (0.29-0.74) 6.18 (3.95-9.22) 0.41 (0.26-0.66)
P   <0.0001 <0.0001 0.194 0.821 0.140
Acute myocardial infarction 949 (11.4) 7.80±1.31 7.86±1.18 0.62±0.45 7.64±5.08 0.54±0.39
7.67 (6.92-8.51) 7.78 (7.05-8.53) 0.49 (0.31-0.77) 6.39 (4.13-9.44) 0.43 (0.27-0.67)
P   <0.0001 <0.0001 0.004 0.068 0.003
Any cerebrovascular event 902 (10.9) 8,00±1.51 7.96±1.24 0.59±0.45 7.18±4.91 0.52±0.40
7.75 (7.02-8.73) 7.83 (7.12-8.64) 0.47 (0.28-0.72) 5.91 (3.74-8.92) 0.41 (0.25-0.64)
P   <0.0001 <0.0001 0.956 0.103 0.672
Stroke 257 (3.1) 7.64±1.37 7.70±1.21 0.59±0.40 7.56±4.86 0.51±0.34
7.45 (6.61-8.43) 7.63 (6.75-8.45) 0.48 (0.30-0.74) 6.28 (4.25-9.40) 0.42 (0.27-0.64)
P   0.470 0.354 0.299 0.381 0.325
Any lower limb vascular event 584 (7.0) 8.02±1.45 8.02±1.19 0.64±0.50 7.68±5.34 0.56±0.45
7.85 (7.09-8.73) 7.92 (7.22-8.66) 0.50 (0.31-0.80) 6.32 (4.10-9.38) 0.45 (0.27-0.69)
P   <0.0001 <0.0001 0.013 0.372 0.005
Ulceration/gangrene 319 (3.8) 7.93±1.55 8.01±1.25 0.71±0.58 8.49±5.93 0.62±0.51
7.67 (6.98-8.62) 7.88 (7.18-8.64) 0.54 (0.34-0.86) 6.76 (4.31-10.23) 0.48 (0.30-0.76)
P   <0.0001 <0.0001 <0.0001 0.004 <0.0001
  1. Current HbA1c, HbA1c-MEAN, HbA1c-SD, HbA1c-CV, and Adj-HbA1c-SD values in patients with any major acute CVD event by vascular bed (coronary, carotid and lower limb) versus subjects without CVD. Values are mean±SD and median (interquartile range); P values for comparison between groups using the Student’s t test for parametric or the corresponding Mann–Whitney U test for nonparametric (HbA1c-SD, HbA1c-CV, and Adj- HbA1c-SD) variables.