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Table 2 Effects of IMD upon Hemodynamic Parameters Measured After MI

From: Intermedin protects against myocardial ischemia-reperfusion injury in diabetic rats

Parameter (units) / Group

NS

NIR

DS

DIR

IMD

LVDP(mmHg)

99.68 ± 2.95

71.81 ± 4.55†

92.91 ± 3.05

60.58 ± 5.47#

82.51 ± 4.53*

+dp/dtmax(mmHg /s)

7584 ± 295.8

5947 ± 354.4†

7012 ± 455.1

3877 ± 256.1#

5565 ± 403.0*

-dp/dtmax(mmHg /s)

5612 ± 148.3

4420 ± 358.9†

5324 ± 213.6

2830 ± 205.1#

4076 ± 280.2*

  1. Abbreviations: NS: non-diabetic sham; NIR: non-diabetic ischemia/reperfusion + vehicle; DS: diabetic sham; DIR: diabetic ischemia/reperfusion + vehicle; IMD: diabetic ischemica/reperfusion group + IMD treatment. Results represent mean ± SEM. †P < 0.05 vs. NS, #P < 0.05 vs. DS, *P < 0.05 vs. DIR. n = 6-12/group.
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Cardiovascular Diabetology

ISSN: 1475-2840