Figure 1
From: Remodelling of the intracardiac ganglia in diabetic Goto-Kakizaki rats: an anatomical study
Intact heart preparations. Dorsal view of the heart from GK (a) and control (b) rats demonstrates the intracardiac ganglia (arrows) and intracardiac nerves stained for acetylcholinesterase. Dotted lines demarcate the cardiac region that was used for quantitative analysis of the nerve density. Boxed areas in a and b are enlarged in panels c and d, respectively. Note that intracardiac ganglia in GK rat (c) are sparse compared to the control rat (d). Several intracardiac ganglia (arrows) from GK (e) and control (f) rats are shown at high magnification with ganglion areas and neuronal numbers indicated nearby ganglia. Neuronal numbers are assessed by linear regression plots as shown in Figure 3a, b. CV, caudal vein; LCV, left cranial vein; LPV, left pulmonary vein; MPV, middle pulmonary vein. Bars 4 mm (a, b), 1 mm (c, d), 0.4 mm (e, f).