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Table 5 Echocardiographic parameters associated with all-cause mortality in a multivariate Cox regression model

From: New concept of myocardial longitudinal strain reserve assessed by a dipyridamole infusion using 2D-strain echocardiography: the impact of diabetes and age, and the prognostic value

Ā 

Univariate analysis

Multivariate analysis

Ā 

HR [95% CI]

p-value

HR [95% CI]

p-value

Rest

Ā Ā Ā Ā 

LVEF (%)

0.889 [0.821 - 0.964]

0.004

Ā Ā 

EDV (ml)

1.019 [1.007 - 1.031]

0.002

Ā Ā 

ESV (ml)

1.020 [1.007 - 1.033]

0.002

Ā Ā 

GLS (%)

1.335 [1.091 ā€“ 1.633]

0.005

Ā Ā 

Stress

Ā Ā Ā Ā 

LVEF (%)

0.898 [0.839 - 0.960]

0.002

Ā Ā 

EDV (ml)

1.026 [1.012 - 1.040]

<0.0001

Ā Ā 

ESV (ml)

1.034 [1.017 - 1.051]

<0.0001

1.047 [1.018 - 1.075]

0.001

GLS (%)

1.481 [1.155 - 1.899]

0.002

Ā Ā 

āˆ† (stress ā€“ rest)

Ā Ā Ā Ā 

āˆ† LVEF (%)

0.962 [0.874 - 1.059]

0.430

Ā Ā 

āˆ† EDV (ml)

1.003 [0.970 - 1.037]

0.862

Ā Ā 

āˆ† ESV (ml)

1.044 [1.006 - 1.084]

0.022

1.065 [1.019 - 1.113]

0.005

LSR (%)

1.395 [0.973 ā€“ 2.001]

0.070

Ā Ā 

LSR > 0

6.012 [1.211 - 29.856]

0.028

15.493 [1.419 - 169.182]

0.025

  1. LVEF = left ventricle ejection fraction; EDV = end diastolic volume; ESV = end systolic volume, TVI LVOT = time-velocity integral in the left ventricular outflow tract, GLS = global longitudinal strain; LSR = longitudinal strain reserve; LSRR = longitudinal strain rate reserve.
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Cardiovascular Diabetology

ISSN: 1475-2840