Common variants in adiponectin gene are associated with coronary artery disease and angiographical severity of coronary atherosclerosis in type 2 diabetes

Table 2 Associations of single nucleotide polymorphisms of ADIPOQ with coronary artery disease

SNPs	Alleles major : minor	MAF		OR (95% CI)	P value
		Control Subjects	CAD Patients
n
rs266729	C : G	0.240	0.338	1.64 (1.35 - 2.01)	0.00095*
rs182052	G : A	0.411	0.423	1.18 (0.98 - 1.52)	0.113
rs16861205	G : A	0.158	0.147	0.82 (0.64 - 1.06)	0.126
rs822396	A : G	0.126	0.131	0.94 (0.72 - 1.23)	0.670
rs12495941	G : T	0.372	0.398	1.04 (0.87 - 1.25)	0.572
rs7627128	C : A	0.238	0.226	0.87 (0.71 - 1.08)	0.217
rs1501299	G : T	0.256	0.238	0.83 (0.67 - 1.03)	0.102
rs3821799	T : C	0.392	0.421	1.07 (0.89 - 1.28)	0.482
rs3774262	G : A	0.288	0.265	0.85 (0.69 - 1.04)	0.129
rs1063539	G : C	0.285	0.302	1.06 (0.87 - 1.30)	0.543
rs12629945	G : A	0.198	0.183	0.83 (0.66 - 1.05)	0.116

MAF, minor allele frequency. All OR and P values are adjusted for age and sex. *P value that can pass multiple testing correction (P < 0.0086).

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