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Table 1 Clinical characteristics of control subjects and CAD patients with type 2 diabetes

From: Common variants in adiponectin gene are associated with coronary artery disease and angiographical severity of coronary atherosclerosis in type 2 diabetes

 

Control Subjects

CAD Patients

P value

n

550

560

 

Age (years)

61.1 ± 7.9

66.0 ± 6.9

< 0.001

Male subjects (%)

42.5

55.4

< 0.001

BMI (kg/m 2 )

22.0 ± 3.4

24.3 ± 3.9

< 0.001

Diabetes duration (years)

10.8 ± 3.6

12.0 ± 4.4

< 0.001

Current smoking (%)

32.0

38.4

0.026

Hypertension (%)

61.8

68.9

0.013

Fasting glucose (mmol/l)

6.49 ± 2.71

6.86 ± 3.10

0.038

2-h post-OGTT glucose (mmol/l)

7.57 ± 1.21

8.40 ± 2.07

< 0.001

HbA1c (%)

7.18 ± 1.01

7.53 ± 1.22

< 0.001

Triglyceride (mmol/l)

1.46 ± 0.21

1.49 ± 0.26

0.023

HDL cholesterol (mmol/l)

1.33 ± 0.28

1.23 ± 0.22

< 0.001

LDL cholesterol (mmol/l)

3.18 ± 0.84

3.25 ± 0.83

0.135

Adiponectin (μg/ml)

7.11 (6.90 - 7.33)

5.90 (5.69 - 6.12)

< 0.001

Gensini score

13.4 (12.6 - 14.2)

22.5 (21.1 - 24.1)

< 0.001

Sullivan Extent score

15.9 (13.9 - 16.6)

28.7 (25.5 - 31.1)

< 0.001

Treatment

   

Diet only (%)

11.3

11.4

0.935

Oral agents (%)

57.6

53.2

0.138

Insulin (%)

31.1

35.4

0.131

  1. Data are expressed as mean ± SD or geometric mean (95% confidence interval). BMI = body mass index; CAD = coronary artery disease; HbA1c = hemoglobin A1C; HDL cholesterol = high-density lipoprotein cholesterol; LDL cholesterol = low-density lipoprotein cholesterol.