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Table 1 Characteristics of patients according to the presence or absence of CAD

From: Serum pigment epithelium-derived factor levels are independently correlated with the presence of coronary artery disease

Parameters

Non-CAD

CAD

P

n (male/female)

84 (43/41)

228 (163/65)

0.001

Age, years

64.0 ± 9.9

67.0 ± 10.0

0.018

Body mass index, kg/m2

24.8 ± 3.9

24.5 ± 3.0

0.520

Waist circumference, cm

89.6 ± 10.9

90.6 ±8.9

0.408

Fasting plasma glucose, mmol/L

5.5 (5.0, 6.0)

5.5 (5.0, 6.4)

0.448

2h postprandial glucose, mmol/L

8.2 (6.2, 9.8)

8.8 (6.7, 12.4)

0.031

Glycated hemoglobin A1c, %

6.0 (5.6, 6.5)

6.2 (5.8, 6.9)

0.005

Fasting insulin, mU/L

16.3(11.9, 22.2)

16.5 (12.0, 24.5)

0.431

HOMA-IR

4.0 (2.8, 6.0)

4.0(2.8, 5.9)

0.939

Systolic blood pressure, mmHg

130.0 (120.0, 150.0)

130 (120.0, 150.0)

0.335

Diastolic blood pressure, mmHg

80.0 (70.0, 85.8)

80.0 (70.0, 83.8)

0.569

Total cholesterol, mmol/L

4.5 ± 1.1

4.3 ± 1.1

0.070

Triglyceride, mmol/L

1.5 (1.0, 2.2)

1.5 (1.1, 2.2)

0.461

HDL-c, mmol/L

1.2 ± 0.3

1.1 ± 0.3

0.018

LDL-c, mmol/L

3.1 ± 0.9

2.9 ± 1.0

0.221

C-reactive protein, mg/L

1.4 (0.6, 3.6)

1.4 (0.6, 4.0)

0.329

Adiponectin, μg/mL

8.4 (5.6, 11,9)

7.1 (4.7, 12.1)

0.113

Serum creatinine, μmol/L

72.0 (61.0, 87.3)

79.0 (68.0, 91.0)

0.008

Uric acid, μmol/L

324.4 ± 85.5

352.3 ± 90.6

0.392

eGFR, mL/min/1.73m2

90.7 ± 25.1

85.5 ± 23.2

0.092

24h urine albumin, mg/d

7.5 (5.1, 14.1)

7.1 (4.9, 18.3)

0.775

CAD family history, n (%)

35 (41.6)

106 (46.5)

0.243

Smoking, n (%)

31 (36.9)

107 (46.9)

0.073

Metabolic syndrome, n (%)

51 (60.7)

146 (64.0)

0.340

Central obesity, n (%)

46 (56.1)

132 (58.9)

0.376

Hyperglycemia, n (%)

51 (60.7)

147 (64.5)

0.314

Hypertension, n (%)

71 (84.5)

206 (90.4)

0.109

Hypertriglyceridemia, n (%)

34 (40.5)

89 (39.0)

0.458

Low HDL-c, n (%)

33 (39.3)

117 (51.3)

0.039

Hypoglycemic therapy, n (%)

12 (14.3)

60 (26.3)

0.016

Anti-hypertensive therapy, n (%)

54 (64.3)

166 (72.8)

0.094

Lipid-lowering therapy, n (%)

11 (13.1)

80 (35.1)

<0.001

  1. Data are mean ± SD or median (interquartile range). CAD, coronary artery disease; eGFR, estimated glomerular filtration rate; HDL-c, high-density lipoprotein cholesterol; HOMA-IR, homeostatic model assessment-insulin resistance; LDL-c, low-density lipoprotein cholesterol.