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Table 1 Characteristics of patients according to the presence or absence of CAD

From: Serum pigment epithelium-derived factor levels are independently correlated with the presence of coronary artery disease

Parameters Non-CAD CAD P
n (male/female) 84 (43/41) 228 (163/65) 0.001
Age, years 64.0 ± 9.9 67.0 ± 10.0 0.018
Body mass index, kg/m2 24.8 ± 3.9 24.5 ± 3.0 0.520
Waist circumference, cm 89.6 ± 10.9 90.6 ±8.9 0.408
Fasting plasma glucose, mmol/L 5.5 (5.0, 6.0) 5.5 (5.0, 6.4) 0.448
2h postprandial glucose, mmol/L 8.2 (6.2, 9.8) 8.8 (6.7, 12.4) 0.031
Glycated hemoglobin A1c, % 6.0 (5.6, 6.5) 6.2 (5.8, 6.9) 0.005
Fasting insulin, mU/L 16.3(11.9, 22.2) 16.5 (12.0, 24.5) 0.431
HOMA-IR 4.0 (2.8, 6.0) 4.0(2.8, 5.9) 0.939
Systolic blood pressure, mmHg 130.0 (120.0, 150.0) 130 (120.0, 150.0) 0.335
Diastolic blood pressure, mmHg 80.0 (70.0, 85.8) 80.0 (70.0, 83.8) 0.569
Total cholesterol, mmol/L 4.5 ± 1.1 4.3 ± 1.1 0.070
Triglyceride, mmol/L 1.5 (1.0, 2.2) 1.5 (1.1, 2.2) 0.461
HDL-c, mmol/L 1.2 ± 0.3 1.1 ± 0.3 0.018
LDL-c, mmol/L 3.1 ± 0.9 2.9 ± 1.0 0.221
C-reactive protein, mg/L 1.4 (0.6, 3.6) 1.4 (0.6, 4.0) 0.329
Adiponectin, μg/mL 8.4 (5.6, 11,9) 7.1 (4.7, 12.1) 0.113
Serum creatinine, μmol/L 72.0 (61.0, 87.3) 79.0 (68.0, 91.0) 0.008
Uric acid, μmol/L 324.4 ± 85.5 352.3 ± 90.6 0.392
eGFR, mL/min/1.73m2 90.7 ± 25.1 85.5 ± 23.2 0.092
24h urine albumin, mg/d 7.5 (5.1, 14.1) 7.1 (4.9, 18.3) 0.775
CAD family history, n (%) 35 (41.6) 106 (46.5) 0.243
Smoking, n (%) 31 (36.9) 107 (46.9) 0.073
Metabolic syndrome, n (%) 51 (60.7) 146 (64.0) 0.340
Central obesity, n (%) 46 (56.1) 132 (58.9) 0.376
Hyperglycemia, n (%) 51 (60.7) 147 (64.5) 0.314
Hypertension, n (%) 71 (84.5) 206 (90.4) 0.109
Hypertriglyceridemia, n (%) 34 (40.5) 89 (39.0) 0.458
Low HDL-c, n (%) 33 (39.3) 117 (51.3) 0.039
Hypoglycemic therapy, n (%) 12 (14.3) 60 (26.3) 0.016
Anti-hypertensive therapy, n (%) 54 (64.3) 166 (72.8) 0.094
Lipid-lowering therapy, n (%) 11 (13.1) 80 (35.1) <0.001
  1. Data are mean ± SD or median (interquartile range). CAD, coronary artery disease; eGFR, estimated glomerular filtration rate; HDL-c, high-density lipoprotein cholesterol; HOMA-IR, homeostatic model assessment-insulin resistance; LDL-c, low-density lipoprotein cholesterol.