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Table 4 Ex vivo cardiac function

From: Preserved endothelium-dependent dilatation of the coronary microvasculature at the early phase of diabetes mellitus despite the increased oxidative stress and depressed cardiac mechanical function ex vivo

 

ZL

ZDF

HR (beats/min)

294 ± 10

171 ± 23*

LVDP (mmHg)

99 ± 6

115 ± 6*

RPP (mHg/min)

29 ± 2

19 ± 2*

CF (ml/min)

14.1 ± 1.0

10.6 ± 0.8*

CP before U46619 (mmHg)

78 ± 8

78 ± 3

CP after U46619 (mmHg)

121 ± 9

130 ± 8

  1. The number of experiments was 11 and 10 for the ZL and ZDF groups respectively. ZL: Zucker lean rats; ZDF: Zucker Diabetic fatty rats; HR: Heart Rate, LVDP: Left Ventricle Developed Pressure, RPP: Rate x Pressure Product, CF: Coronary Flow, CP: Coronary Pressure. * significantly different.