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Table 3 Fatty acid composition of cardiac phospholipids

From: Preserved endothelium-dependent dilatation of the coronary microvasculature at the early phase of diabetes mellitus despite the increased oxidative stress and depressed cardiac mechanical function ex vivo

Fatty acids (%)

ZL

ZDF

14:0

0.07 ± 0.01

0.05 ± 0.01*

DMA16:0

2.67 ± 0.15

4.39 ± 0.60*

16:0

12.63 ± 0.17

13.25 ± 0.58

DMA18:0

1.20 ± 0.06

1.29 ± 0.25

18:0

19.37 ± 0.50

25.70 ± 1.12*

SFA

35.94 ± 0.80

44.68 ± 1.07*

16:1n-7

0.56 ± 0.02

0.37 ± 0.02*

18:1n-9

3.49 ± 0.16

2.53 ± 0.08*

18:1n-7

5.77 ± 0.22

3.32 ± 0.10*

MUFA

9.81 ± 0.36

6.21 ± 0.16*

18:2n-6

32.94 ± 1.83

15.65 ± 2.57*

20:2n-6

0.17 ± 0.02

0.17 ± 0.01

20:3n-6

0.40 ± 0.05

1.01 ± 0.11*

20:4n-6

16.01 ± 0.83

23.62 ± 1.64*

22:4n-6

0.42 ± 0.04

0.38 ± 0.03

22:5n-6

0.31 ± 0.01

0.39 ± 0.04

n-6 PUFA

50.25 ± 0.94

41.23 ± 1.27*

20:5n-3

0.10 ± 0.01

0.08 ± 0.06

22:5n-3

0.55 ± 0.06

1.26 ± 0.11*

22:6n-3

3.31 ± 0.41

6.51 ± 0.55*

n-3 PUFA

3.95 ± 0.43

7.86 ± 0.64*

PUFA

54.20 ± 0.63

49.09 ± 1.17*

n-6/n-3

13.51 ± 1.70

5.40 ± 0.47*

Total 16:0

15.30 ± 0.28

17.63 ± 0.30*

Total 18:0

20.57 ± 0.54

26.00 ± 0.94*

Total 18:1

9.26 ± 0.35

5.87 ± 0.16*

EPA/AA

0.006 ± 0.001

0.004 ± 0.001*

EPA + DHA

3.4 ± 0.4

6.6 ± 0.6*

  1. Values are expressed as relative amounts of the total fatty acid content. The analysis was performed on 5 samples randomly selected in each group. ZL: Zucker lean rats; ZDF: Zucker diabetic fatty rats; DMA: dimethylacetal; SFA: saturated fatty acids; MUFA: monounsaturated fatty acids; PUFA: polyunsaturated fatty acids; EPA: eicosapentanoic acid; AA: arachidonic acid; DHA: docosahexaenoic acid; *: significantly different.