Coronary microvascular reactivity ex vivo. (A) Endothelial-dependent dilatation (EDD). (B) Endothelial-independent dilatation (EID). (C) Endothelial cell vasodilatation activity (ECVA). ZL: Zucker lean rats; ZDF: Zucker Diabetic Fatty rats; Ach: acetylcholine; SNP: sodium nitroprusside. The number of experiments was 11 and 10 for the ZL and ZDF groups respectively. *: significantly different.