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Figure 3 | Cardiovascular Diabetology

Figure 3

From: Antidiabetic treatment restores adiponectin serum levels and APPL1 expression, but does not improve adiponectin-induced vasodilation and endothelial dysfunction in Zucker diabetic fatty rats

Figure 3

Dose-dependent relaxation of resistance arteries to cumulative doses of adiponectin with and without L-NAME after precontraction with norepinephrine exemplary for ZL and ZDF rats. Adiponectin-induced vasodilation is nearly totally blunted by L-NAME indicating NO-dependency of vasodilation. Two-way ANOVA for repeated measurements: * p < 0.001 vs. ZL+L-NAME; # p < 0.001 vs. ZDF+L-NAME.

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Cardiovascular Diabetology

ISSN: 1475-2840