Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker

Table 1 Body, heart and left ventricle weights, blood pressure, heart rate and lipid profile

Parameter	Control group (n = 7)	HSu group (n = 7)
Body, heart and LV weights
BW (g)	390.40 ± 8.45	397.40 ± 8.71
HW (g)	0.89 ± 0.09	1.10 ± 0.01*
LVW (g)	0.45 ± 0.02	0.53 ± 0.02***
HW/BW (g/kg)	2.14 ± 0.23	2.62 ± 0.07
LVW/BW (g/kg)	1.07 ± 0.02	1.28 ± 0.04**
Blood pressure and heart rate
SBP (mmHg)	122.00 ± 1.79	121.60 ± 1.10
DBP (mmHg)	100.10 ± 1.55	98.40 ± 1.32
MBP (mmHg)	108.80 ± 1.27	109.80 ± 1.23
HR (beats/min)	356.70 ± 1.00	368.90 ± 8.14
Lipid profile
TGs (mg/dl)	68.14 ± 9.96	143.10 ± 23.23*
TC (mg/dl)	63.71 ± 0.94	58.25 ± 3.44

Data are expressed as mean ± SEM, *P < 0.05; ** P < 0.01; ***P < 0.001 versus Control. BW: body weight; DBP: diastolic blood pressure; HR: heart rate; HW: heart weight; LVW: left ventricular weight; MBP: mean blood pressure; SBP: systolic blood pressure; TC: total cholesterol; TGs: triglycerides.

ISSN: 1475-2840