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Figure 6 | Cardiovascular Diabetology

Figure 6

From: Impaired cardioprotective function of transplantation of mesenchymal stem cells from patients with diabetes mellitus to rats with experimentally induced myocardial infarction

Figure 6

Protein expression in infarcted myocardium. (A) Immunohistochemical detection of Bcl-2 expression in infarcted myocardium from control (+), CAD+DM (++) and CAD (+++) groups. (B) Western-blot analysis shows that hMSCs transplantation from patients with CAD+DM and CAD significantly increased Bcl-2 expression in the myocardium compared with the control group. However, Bcl-2 protein level was significantly lower in the CAD+DM group than in the CAD group. (C) Western-blot analysis shows that VEGF expression after hMSCs transplantation in CAD+DM group was significantly lower than in the CAD group. (*P < 0.05 vs. control group, #P < 0.05 vs. CAD group).

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Cardiovascular Diabetology

ISSN: 1475-2840