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Table 3 Adverse events

From: Effects of sitagliptin beyond glycemic control: focus on quality of life

Event

Number

Death (cause unknown)

1

Worsening of vomiting, stomachache, constipation

1

Loss of consciousness

1

Hypoglycemia

1

Intestinal tuberculosis, pneumonia

1

Stool abnormality

2

Acute myocardial infarction

1

Thrombocytopenia

1

Worsening of heart failure

1

New onset of dyslipidemia

3

Bleeding or ulcer of GI tract

2

Liver dysfunction

4

Elevation of CPK

2

Fever and poor physical health

1

Skin disease including eruption

2

Total number of incidents

24 in 23 subjects

  1. GI, gastric intestinal; CPK, creatinine phosphokinase.
  2. Liver dysfunction is defined as elevated (> 2.5 × the upper limit of normal) alanine aminotransferase or aspartate aminotransferase.
  3. Elevation of CPK is defined as elevated > 2 × the upper limit of normal.
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Cardiovascular Diabetology

ISSN: 1475-2840