ADPβS-induced relaxation with and without LNAME. Concentration dependent relaxation of ADPβS with and without LNAME on thoracic aorta rings obtained from sedentary control (SC) and sedentary diabetic (SD) groups precontracted with PE. Tension is expressed as % relaxation on initial contraction with PE. Values are expressed as mean ±SEM. *** = p<0.001 significantly different from (SC). ‡ ‡ ‡ = p<0.001 significantly different from (SD), groups.