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Figure 4 | Cardiovascular Diabetology

Figure 4

From: Intense exercise training is not effective to restore the endothelial NO-dependent relaxation in STZ-diabetic rat aorta

Figure 4

(a) ACh-induced relaxation with and without LNAME in sedentary and trained control. Concentration dependent relaxation of acetylcholine (ACh) with and without LNAME on thoracic aorta rings obtained from sedentary control (SC), trained control (TC) group precontracted with PE. Tension is expressed as % relaxation on initial contraction with PE. Values are expressed as mean ±SEM. * significantly different from sedentary control rats (p<0.05), † significantly different from trained control rats. (b) ACh-induced relaxation with and without LNAME in sedentary and trained STZ-diabetic rats. Concentration dependent relaxation of acetylcholine (ACh) with and without LNAME on thoracic aorta rings obtained from sedentary diabetic (SD) and trained diabetic (TD) groups precontracted with PE. Tension is expressed as % relaxation on initial contraction with PE. Values are expressed as mean ±SEM. ‡ Significantly different from sedentary diabetic rats (p<0.05). Significantly different from trained diabetic rats (p<0.05).

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