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Figure 3 | Cardiovascular Diabetology

Figure 3

From: Treatment with a copper-selective chelator causes substantive improvement in cardiac function of diabetic rats with left-ventricular impairment

Figure 3

Time- and treatment-dependent changes in cMRI-derived cardiac functional parameters during the 16-week experimental period in groups of control (n = 12), untreated-diabetic (n = 12) and trientine-treated diabetic (n = 13) adult male rats. Drug treatment was initiated after the measurements of Week 8 (arrowed in A, B): A, LV ejection fraction (LVEF); B, LV cardiac output (CO); C, Ratio of CO/LV mass (CO/LVM); D, ratio of CO to body-weight (CO/BW). Abbreviation: TETA, triethylenetetramine.

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