Table 3 Unadjusted and least-square adjusted mean concentrations (standard error) of lipids and apolipoprotein B among adults aged > =20 years, by glycemic status and survey, National Health and Nutrition Examination Survey 1988–1991 and 2005–2006
Diagnosed diabetes | Undiagnosed diabetes | Prediabetes | Normal | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
1988-1991 | 2005-2008 | P* | 1988-1991 | 2005-2008 | P* | 1988-1991 | 2005-2008 | P* | 1988-1991 | 2005-2008 | P* | |
N | 200 | 211 | 91 | 67 | 545 | 634 | 2302 | 2290 | ||||
Unadjusted | ||||||||||||
Total cholesterol (mg/dl) | 214.4 (3.7) | 194.6 (3.2) | <0.001 | 224.5 (5.0) | 208.8 (6.0) | 0.051 | 217.5 (1.7) | 209.9 (2.2) | 0.008 | 199.9 (1.3) | 196.0 (1.2) | 0.034 |
High-density lipoprotein cholesterol (mg/dl) | 48.8 (1.6) | 51.2 (1.5) | 0.287 | 44.8 (1.8) | 46.3 (2.0) | 0.580 | 48.1 (0.7) | 53.5 (0.9) | <0.001 | 51.8 (0.7) | 55.9 (0.5) | <0.001 |
Low-density lipoprotein cholesterol (mg/dl) | 134.7 (3.0) | 113.8 (2.6) | <0.001 | 144.8 (3.9) | 130.0 (5.3) | 0.028 | 142.2 (1.8) | 129.8 (1.6) | <0.001 | 124.3 (1.3) | 116.7 (1.1) | <0.001 |
Non-high-density lipoprotein cholesterol (mg/dl) | 165.6 (4.6) | 143.5 (3.2) | <0.001 | 179.7 (4.5) | 162.5 (5.5) | 0.019 | 169.4 (1.8) | 156.4 (2.1) | <0.001 | 148.1 (1.5) | 140.1 (1.2) | <0.001 |
Triglycerides (mg/dl)† | 154.5 (9.8) | 148.1 (7.4) | 0.604 | 174.0 (10.4) | 163.2 (11.9) | 0.496 | 135.9 (4.3) | 135.8 (3.7) | 0.987 | 118.8 (3.6) | 116.9 (1.7) | 0.639 |
Triglycerides (mg/dl)‡ | 139.1 (9.9) | 131.2 (7.1) | 0.513 | 158.3 (9.6) | 140.6 (12.1) | 0.263 | 120.9 (3.7) | 120.5 (3.0) | 0.936 | 103.8 (3.2) | 102.3 (1.6) | 0.674 |
Apolipoprotein B (mg/dl) | 113.8 (2.8) | 103.2 (2.4) | 0.005 | 121.7 (3.1) | 116.9 (3.6) | 0.321 | 115.1 (1.2) | 109.6 (1.3) | 0.003 | 101.6 (0.9) | 98.7 (1.0) | 0.041 |
Age-adjusted | ||||||||||||
Total cholesterol (mg/dl) | 202.5 (3.7) | 185.8 (3.6) | 0.002 | 212.9 (4.4) | 198.4 (6.3) | 0.070 | 207.4 (1.8) | 202.1 (2.0) | 0.048 | 201.6 (1.2) | 198.5 (1.1) | 0.062 |
High-density lipoprotein cholesterol (mg/dl) | 46.9 (1.6) | 49.7 (1.5) | 0.202 | 42.9 (1.8) | 44.6 (2.0) | 0.528 | 46.5 (0.7) | 52.2 (0.9) | <0.001 | 52.1 (0.7) | 56.3 (0.4) | <0.001 |
Low-density lipoprotein cholesterol (mg/dl) | 126.6 (2.9) | 107.8 (2.9) | <0.001 | 137.0 (3.7) | 122.9 (5.7) | 0.046 | 135.3 (1.9) | 124.5 (1.5) | <0.001 | 125.5 (1.3) | 118.4 (1.1) | <0.001 |
Non-high-density lipoprotein cholesterol (mg/dl) | 155.6 (4.5) | 136.1 (3.6) | 0.001 | 170.0 (4.1) | 153.8 (5.7) | 0.028 | 160.9 (2.0) | 149.9 (2.0) | <0.001 | 149.5 (1.4) | 142.2 (1.2) | <0.001 |
Triglycerides (mg/dl)† | 145.2 (9.6) | 141.2 (7.6) | 0.743 | 164.9 (10.0) | 155.0 (11.5) | 0.518 | 127.9 (4.4) | 129.7 (3.6) | 0.755 | 120.2 (3.6) | 118.9 (1.7) | 0.750 |
Triglycerides (mg/dl)‡ | 127.6 (9.0) | 123.1 (6.9) | 0.683 | 145.6 (8.5) | 130.4 (11.0) | 0.283 | 112.3 (3.4) | 113.9 (2.6) | 0.713 | 105.1 (3.2) | 104.2 (1.6) | 0.797 |
Apolipoprotein B (mg/dl) | 107.8 (2.7) | 98.7 (2.6) | 0.019 | 115.8 (2.9) | 111.6 (3.8) | 0.388 | 109.9 (1.4) | 105.7 (1.2) | 0.018 | 102.4 (0.9) | 100.0 (0.9) | 0.066 |
Adjusted for age, gender, race or ethnicity, education, and body mass index | ||||||||||||
Total cholesterol (mg/dl) | 201.7 (3.5) | 183.7 (3.4) | <0.001 | 211.3 (4.7) | 193.9 (6.2) | 0.029 | 208.0 (1.9) | 200.7 (2.1) | 0.010 | 202.2 (1.2) | 198.4 (1.0) | 0.018 |
High-density lipoprotein cholesterol (mg/dl) | 48.0 (1.2) | 52.9 (1.4) | 0.009 | 46.8 (2.1) | 51.0 (2.5) | 0.213 | 47.0 (0.7) | 53.9 (0.8) | <0.001 | 51.2 (0.6) | 56.3 (0.4) | <0.001 |
Low-density lipoprotein cholesterol (mg/dl) | 125.6 (2.7) | 104.8 (2.8) | <0.001 | 133.7 (4.3) | 116.3 (5.6) | 0.016 | 135.0 (2.0) | 122.5 (1.5) | <0.001 | 126.2 (1.2) | 118.5 (0.9) | <0.001 |
Non-high-density lipoprotein cholesterol (mg/dl) | 153.7 (4.0) | 130.8 (3.4) | <0.001 | 164.5 (5.3) | 143.0 (5.9) | 0.009 | 160.9 (2.0) | 146.9 (2.0) | <0.001 | 150.9 (1.2) | 142.1 (0.9) | <0.001 |
Triglycerides (mg/dl)† | 140.6 (8.2) | 129.7 (7.4) | 0.324 | 154.1 (11.9) | 134.0 (13.2) | 0.258 | 129.6 (3.7) | 124.4 (3.8) | 0.319 | 123.4 (3.2) | 118.1 (1.6) | 0.141 |
Triglycerides (mg/dl)‡ | 122.9 (7.3) | 111.7 (6.0) | 0.224 | 133.2 (10.3) | 109.4 (10.4) | 0.107 | 114.3 (2.7) | 109.0 (2.5) | 0.148 | 108.0 (2.8) | 103.4 (1.4) | 0.146 |
Apolipoprotein B (mg/dl) | 106.4 (2.6) | 95.0 (2.5) | 0.002 | 111.8 (3.2) | 104.2 (4.0) | 0.148 | 109.6 (1.5) | 103.5 (1.2) | 0.002 | 103.4 (0.9) | 100.0 (0.7) | 0.006 |