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Table 4 The risk of carotid atherosclerotic plaques associated with 1 SD decrease in osteocalcin

From: Serum osteocalcin level and its association with carotid atherosclerosis in patients with type 2 diabetes

 

Model

PLQ

p valuea

Total

Model 1

1.93 (1.32-3.01)

<0.001

Model 2

1.86 (1.31-2.95)

<0.001

Model 3

1.82 (1.28-2.94)

<0.001

Model 4

1.81(1.24-2.82)

<0.001

Model 5

1.76 (1.22-2.77)

0.005

men

Model 1

2.13 (1.41-3.69)

<0.001

Model 2

2.02 (1.50-3.57)

<0.001

Model 3

1.91 (1.32-2.88)

<0.001

Model 4

1.83(1.27-2.85)

<0.001

Model 5

1.81 (1.25-2.83)

<0.001

women

Model 1

1.88 (1.29-3.12)

<0.001

Model 2

1.84 (1.27-2.99)

<0.001

Model 3

1.80 (1.24-2.98)

<0.001

Model 4

1.79(1.22-2.92)

<0.001

 

Model 5

1.75 (1.19-2.85)

0.008

  1. Values are ORs (95% CI).
  2. Model 1: Unadjusted. Model 2: Adjusted for age, sex, smoking (yes/no), alcohol drinking (yes/no), family history of diabetes (yes/no). Model 3: Further adjusted for waist circumference, HOMA-IR, BMI and waist/hip ratio. Model 4: Further adjusted for serum triacylglycerol, total cholesterol, HDL- and LDL-cholesterol. Model 5: Further adjusted for inflammatory factors (CRP) and treatments (including antihypertensive therapy, antihyperlipidemic therapy and antihyperglycemic therapy). aFor the risk of PLQ, we defined subjects with no carotid atherosclerotic plaques as 0, and carotid atherosclerotic plaques as 1 from the analysis.