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Table 4 Associations of serum 25(OH)D and LPL with IR and T2D

From: Lipoprotein lipase links vitamin D, insulin resistance, and type 2 diabetes: a cross-sectional epidemiological study

 

25(OH)D (ng/ml)

Quartiles of LPL (U/L)

 

Deficiency

Insufficiency

Sufficiency

Q 1

Q 2

Q 3

Q 4

 

(< 20.0)

(20.1-29.9)

(≥ 30.0)

(≤ 532.8)

(532.9-653.2)

(653.3-778.6)

(> 778.6)

IR, OR (95% CI)

Cases/Non-cases

101/321

324/1278

103/581

159/518

143/534

128/549

98/579

Model 1

1.91 (1.23-2.76)

1.42 (1.04-1.87)

1.00 (reference)

1.85 (1.22-2.68)

1.51 (1.03-2.25)

1.32 (0.91-1.93)

1.00 (reference)

Model 2

1.35 (1.12-2.45)

1.13 (1.02-1.82)

1.00 (reference)

NA

NA

NA

NA

T2D, OR (95% CI)

Cases/Non-cases

87/335

269/1333

76/608

124/553

113/564

101/576

94/583

Model 1

2.06 (1.37-3.24)

1.57 (1.12-2.29)

1.00 (reference)

1.65 (1.14-2.38)

1.41 (1.07-2.25)

1.29 (0.84-1.96)

1.00 (reference)

Model 2

1.42 (1.09-2.68)

1.10 (1.03-1.93)

1.00 (reference)

NA

NA

NA

NA

  1. Model 1, adjusted for age, sex, BMI, PAL, smoking and alcohol consumption.
  2. Model 2, adjusted for covariates in model 1 + LPL.
  3. 25(OH)D, 25-hydroxyvitamin D; IR, insulin resistance; T2D, type 2 diabetes; LPL, lipoprotein lipase; PAL, physical activity level.