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Table 4 Associations of serum 25(OH)D and LPL with IR and T2D

From: Lipoprotein lipase links vitamin D, insulin resistance, and type 2 diabetes: a cross-sectional epidemiological study

  25(OH)D (ng/ml) Quartiles of LPL (U/L)
  Deficiency Insufficiency Sufficiency Q 1 Q 2 Q 3 Q 4
  (< 20.0) (20.1-29.9) (≥ 30.0) (≤ 532.8) (532.9-653.2) (653.3-778.6) (> 778.6)
IR, OR (95% CI)
Cases/Non-cases 101/321 324/1278 103/581 159/518 143/534 128/549 98/579
Model 1 1.91 (1.23-2.76) 1.42 (1.04-1.87) 1.00 (reference) 1.85 (1.22-2.68) 1.51 (1.03-2.25) 1.32 (0.91-1.93) 1.00 (reference)
Model 2 1.35 (1.12-2.45) 1.13 (1.02-1.82) 1.00 (reference) NA NA NA NA
T2D, OR (95% CI)
Cases/Non-cases 87/335 269/1333 76/608 124/553 113/564 101/576 94/583
Model 1 2.06 (1.37-3.24) 1.57 (1.12-2.29) 1.00 (reference) 1.65 (1.14-2.38) 1.41 (1.07-2.25) 1.29 (0.84-1.96) 1.00 (reference)
Model 2 1.42 (1.09-2.68) 1.10 (1.03-1.93) 1.00 (reference) NA NA NA NA
  1. Model 1, adjusted for age, sex, BMI, PAL, smoking and alcohol consumption.
  2. Model 2, adjusted for covariates in model 1 + LPL.
  3. 25(OH)D, 25-hydroxyvitamin D; IR, insulin resistance; T2D, type 2 diabetes; LPL, lipoprotein lipase; PAL, physical activity level.