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Table 3 Association of plasma copeptin levels and IMT

From: Plasma copeptin levels are inversely associated with intima-media-thickness in men: the population-based KORA F4 study

  Copeptin Copeptin Copeptin β per 1 SD increase in copeptin
Q3-4 vs Q1-2 Q4 vs Q1-Q3 Q4 vs Q1
No adjustment  
All subjects (N = 1,275) 0.010 0.023 0.028 0.005
(-0.005; 0.026) (0.005; 0.041) (0.006; 0.050) (-0.003; 0.013)
Men (N = 624) -0.013 0.016 0.009 0.002
(-0.036; 0.011) (-0.011; 0.043) (-0.024; 0.042) (-0.010; 0.014)
Women (N = 651) 0.032 0.030 0.046 0.008
(0.012; 0.052) (0.007; 0.053) (0.018; 0.074) (-0.002; 0.018)
Adjusted for age and sex  
All subjects -0.018 -0.011 -0.015 -0.001
(-0.030; -0.006) (-0.025; 0.003) (-0.033; 0.002) (-0.007; 0.005)
Men -0.042 -0.028 -0.038 -0.009
(-0.060; -0.023) (-0.049; -0.006) (-0.064; -0.011) (-0.018; 0.001)
Women 0.005 0.004 0.006 0.005
(-0.011; 0.020) (-0.013; 0.022) (-0.016; 0.027) (-0.002; 0.013)
Adjusted for age, sex and BMI  
All subjects -0.018 -0.012 -0.016 -0.002
(-0.030; -0.006) (-0.026; 0.002) (-0.033; 0.0005) (-0.008; 0.004)
Men -0.039 -0.026 -0.035 -0.009
(-0.057; -0.020) (-0.048; -0.005) (-0.061; -0.009) (-0.018; 0.0002)
Women 0.002 0.002 0.003 0.004
(-0.013; 0.018) (-0.016; 0.020) (-0.019; 0.024) (-0.003; 0.012)
Multivariable adjustment a  
All subjects -0.022 -0.014 -0.020 -0.003
(-0.034; -0.010) (-0.028; -0.0002) (-0.037; -0.003) (-0.009; 0.003)
Men -0.038 -0.024 -0.035 -0.010
(-0.057; -0.020) (-0.046; -0.002) (-0.062; -0.009) (-0.020; -0.001)
Women -0.002 -0.001 -0.001 0.004
(-0.017; 0.014) (-0.019; 0.017) (-0.023; 0.021) (-0.004; 0.012)
  1. Gender-specific adjusted β’s (95% CI) for IMT given in mm as dependent variable and categories of copeptin as independent variable (highest quartile Q4 or Q3-4 versus lower quartiles (reference)): Results of linear regression models.
  2. aAdjusted for: age, sex, BMI, waist (continuous), hypertension (systolic blood pressure ≥ 140/90 mm Hg or antihypertensive medication), HDL cholesterol (continuous), LDL cholesterol (continuous), triglycerides (continuous), former myocardial infarction or stroke, smoking (active/former/never), alcohol consumption (abstinent/moderate/high), physical activity (high/low), hsCRP, eGFR, prediabetes (yes/no), T2D (yes/no).
  3. bold: p < 0.05.