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Table 1 Baseline characteristics of subjects by the haemoglobin A1c levels and group with antidiabetic medication

From: Haemoglobin A1c even within non-diabetic level is a predictor of cardiovascular disease in a general Japanese population: the Hisayama Study

 

HbA1c level (%)

Antidiabetic medication

≤ 5.0

5.1–5.4

5.5–6.4

≤ 6.5

Variables

(n = 955)

(n = 923)

(n = 736)

(n = 104)

(n = 133)

Age (years)

56 (11)

59 (10)

61 (10)

60 (10)

65 (9)

Men (%)

46.0

38.1

41.9

47.1

56.4

Fasting plasma glucose (mmol/L)*

5.6 (0.5)

5.8 (0.5)

6.2 (0.8)

9.2 (2.6)

8.7 (2.0)

2-hour postload glucose (mmol/L)*

6.5 (1.5)

7.1 (1.9)

8.6 (3.1)

16.9 (5.3)

17.1 (4.7)

Systolic blood pressure (mmHg)

128 (20)

129 (19)

135 (21)

143 (22)

139 (22)

Diastolic blood pressure (mmHg)

77 (12)

78 (12)

80 (12)

84 (13)

81 (12)

Hypertension (%)

33.5

35.8

49.3

54.8

69.9

ECG abnormalities (%)

15.5

12.2

17.7

18.3

14.3

Body mass index (kg/m2)

22.4 (2.9)

23.3 (3.2)

24.0 (3.6)

25.8 (4.3)

23.8 (3.4)

Total cholesterol (mmol/l)

5.12 (0.90)

5.37 (0.90)

5.41 (0.94)

5.62 (0.91)

5.29 (0.94)

HDL cholesterol (mmol/l)

1.70 (0.44)

1.62 (0.41)

1.56 (0.39)

1.46 (0.39)

1.58 (0.42)

Current smoking (%)

27.2

22.0

20.2

26.0

18.8

Current alcohol use (%)

52.7

44.0

39.3

48.1

44.4

Regular exercise (%)

10.6

8.8

12.8

8.7

15.8

  1. Abbreviations: HbA1c, Haemoglobin A1c; ECG, Electrocardiogram; HDL, High-density lipoprotein.
  2. All values are given as means (SD) or as percentages.
  3. *These parameters were measured in only 2,412 subjects who underwent a 75 g oral glucose tolerance test.