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Figure 8 | Cardiovascular Diabetology

Figure 8

From: Protein kinase RNA- like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)- mediated endoplasmic reticulum stress- induced apoptosis in diabetic cardiomyopathy

Figure 8

Immunoblots of proteins obtained from subcellular fractionations of cardiomyocytes. ER, mitochondria and MAMs fractions are isolated from whole cell lysates from cardiomyocytes. Antibodies against IRE1, ATF6 and PERK are used to detect the protein expressions of IRE1, ATF6 and PERK in cellular fractions of ER, MAMs and mitochondria. Sigma R1 is introduced as a internal reference.

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Cardiovascular Diabetology

ISSN: 1475-2840