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Figure 4 | Cardiovascular Diabetology

Figure 4

From: Dipeptidyl peptidase-4 inhibitors and GLP-1 reduce myocardial infarct size in a glucose-dependent manner

Figure 4

Ex-vivo myocardial infarct size expressed as a percentage of the risk zone. (A) There was no difference in myocardial infarct to area at risk ratio (I/R%) in hearts perfused with buffer containing glucose at either 5, 7, 9, or 11 mmol/L. *P < 0.05. N ≥ 6/group. (B) Perfusion of isolated rat hearts with buffer containing GLP-1 reduced myocardial infarct to area at risk ratio (I/R%) in hearts perfused with buffer containing glucose at 7, 9, or 11 mmol/L but not at 5 mmol/L. *P < 0.05. N ≥ 6/group.

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Cardiovascular Diabetology

ISSN: 1475-2840