Parameters | SHR (n = 13) | SHR-DM (n = 12) | P value |
---|
DT (g/mm2) | 5.60 (2.57 – 7.99) | 3.05 (2.17 – 5.42) | 0.121 |
RT (g/mm2) | 0.92 ± 0.37 | 0.81 ± 0.27 | 0.383 |
TPT (ms) | 236 ± 30 | 264 ± 24 | 0.024 |
+dT/dt (g/mm²/s) | 43.2 ± 22.5 | 25.7 ± 15.4 | 0.033 |
-dT/dt (g/mm²/s) | 19.5 ± 9.54 | 15.3 ± 6.96 | 0.229 |
CSA (mm2) | 1.04 ± 0.38 | 1.13 ± 0.30 | 0.511 |
- Data are expressed as mean ± standard deviation or median and 25th and 75th percentile. SHR: spontaneously hypertensive rats without diabetes mellitus; SHR-DM: SHR with diabetes mellitus; DT: peak developed tension; RT: resting tension; TPT: time to peak tension; +dT/dt: maximum tension development rate; -dT/dt: maximum tension decline rate; CSA: papillary muscle cross sectional area. P value: result of statistical test (Student’s t or Mann-Whitney tests).