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Table 2 Echocardiographic structural data

From: Diabetes mellitus activates fetal gene program and intensifies cardiac remodeling and oxidative stress in aged spontaneously hypertensive rats

Parameters

SHR (n = 21)

SHR-DM (n = 16)

P value

HR (bpm)

322 ± 40

287 ± 40

0.010

LVDD (mm)

8.56 ± 1.03

8.73 ± 0.77

0.572

LVDD/BW (mm/kg)

24.2 (22.1 – 26.0)

31.2 (25.3 – 34.0)

0.001

LVDD/T (mm/cm)

2.02 ± 0.24

2.09 ± 0.19

0.445

LVSD (mm)

4.71 ± 1.27

5.54 ± 1.19

0.043

PWT (mm)

1.83 (1.75 – 1.90)

1.72 (1.66 – 1.79)

0.031

SWT (mm)

1.86 (1.77 – 1.91)

1.74 (1.66 – 1.83)

0.023

AO (mm)

4.50 (4.45 – 4.85)

4.45 (4.30 – 4.90)

0.701

LA (mm)

7.46 ± 1.12

7.51 ± 1.27

0.900

LA/BW (mm/kg)

21.5 ± 3.72

26.3 ± 5.82

0.003

LA/T (mm/cm)

1.75 ± 0.22

1.82 ± 0.33

0.513

LV mass (g)

1.24 (1.05 – 1.39)

1.18 (1.05 – 1.41)

0.673

LV mass/BW (g/Kg)

3.35 (3.12 – 4.04)

4.16 (3.27 – 5.05)

0.088

RWT

0.44 ± 0.07

0.40 ± 0.05

0.046

Tibia length (cm)

4.15 (4.10-4.19)

4.20 (4.10-4.20)

0.213

  1. Data are expressed as mean ± standard deviation or median and 25th and 75th percentile. SHR: spontaneously hypertensive rats without diabetes mellitus; SHR-DM: SHR with diabetes mellitus; BW: body weight; HR: heart rate; LVDD and LVSD: left ventricular (LV) diastolic and systolic diameter, respectively; PWT: LV posterior wall thickness; SWT: LV septal wall thickness; AO: aortic diameter; LA: left atrial diameter; LV mass: LV mass; RWT: relative wall thickness; T: tibia length. P value: result of statistical test (Student’s t or Mann-Whitney tests).