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Table 2 Plasma AGE-levels in individuals with and without T1DM

From: Plasma levels of advanced glycation endproducts are associated with type 1 diabetes and coronary artery calcification

  

Model 1

Model 2

  

Mean

95%-CI

p-value

Mean

95%-CI

p-value

Pentosidine* (nmol/mmol LYS)

control

0.51

0.48 – 0.53

 

0.51

0.48 – 0.54

 

T1DM

0.69

0.65 – 0.73

<0.001

0.69

0.65 – 0.73

<0.001

CML (nmol/mmol LYS)

control

92.3

89.6 – 94.9

 

92.6

90.1 – 95.1

 

T1DM

104.8

102.1 – 107.5

<0.001

104.5

102.0 – 107.0

<0.001

CEL (nmol/mmol LYS)

control

14.5

14.0 – 15.0

 

14.6

14.1 – 15.2

 

T1DM

15.0

14.5 – 15.5

0.212

14.9

14.4 – 15.4

0.489

THP* (U/mL)

control

112.7

106.2 – 119.7

 

112.7

105.7 – 119.9

 

T1DM

125.6

118.0 – 133.4

0.015

125.6

117.8 – 134.0

0.025

  1. Data are presented as adjusted means or geometric means* of AGEs in individuals with and without T1DM, by use of a complete case analysis.
  2. n = 169 for individuals without and n = 165 for individuals with T1DM.
  3. Model 1 was adjusted for age and sex. Model 2 was adjusted for age, sex, SBP, DBP, BMI, WHR, pack-years of smoking, LDL, HDL, triglycerides and eGFR.
  4. CML, N(epsilon)-(carboxymethyl)lysine; CEL, N(epsilon)-(carboxyethyl)lysine; THP, tetrahydropyrimidine.
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Cardiovascular Diabetology

ISSN: 1475-2840