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Table 1 Effect of GAlbudAb on post-ischemic left ventricle hemodynamic

From: Novel fusion of GLP-1 with a domain antibody to serum albumin prolongs protection against myocardial ischemia/reperfusion injury in the rat

Parameter

Vehicle

GAlbudAb (2 mg/kg)

N

8

9

LVSP (mmHg)

107 ± 3.0

112 ± 2.6

LVEDP (mmHg)

12.8 ± 1.0

8.6 ± 1.5*

HR (bpm)

425 ± 5

419 ± 10

dP/dtmax (mmHg/s)

6628 ± 273

7612 ± 219*

dP/dtmin (mmHg/s)

5682 ± 311

6746 ± 341*

  1. N, number of animals; LVSP, left ventricle systolic pressure; LVEDP, left ventricle end diastolic pressure; HR, heart rate; dP/dtmax, maximum rates of change in the left ventricle pressure; dP/dtmin, minimum rates of change in left ventricle pressure. Data are presented as mean ± SEM. *p < 0.05 vs. vehicle.
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Cardiovascular Diabetology

ISSN: 1475-2840