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Figure 4 | Cardiovascular Diabetology

Figure 4

From: Interferon regulatory factor-1 together with reactive oxygen species promotes the acceleration of cell cycle progression by up-regulating the cyclin E and CDK2 genes during high glucose-induced proliferation of vascular smooth muscle cells

Figure 4

Comparison of cell proliferation in transfected VSMCs following treatment with NAC, H 2 O 2 or U0126. a: cell numbers were counted with a hemocytometer; b: cell proliferation was also measured using the EdU assay; the presented data are the mean ± SD of triplicate determinations repeated in four separate experiments. High glucose/NAC = cells incubated with high glucose and NAC for 5 days; normal glucose/H2O2 = cells incubated with normal glucose and H2O2 for 5 days; High glucose/U0126 = cells incubated with high glucose and U0126 for 5 days; normal glucose/H2O2/U0126 = cells incubated with normal glucose, H2O2 and U0126 for 5 days. *P <0.05; **P <0.01 versus corresponding values in untransfected VSMCs.

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Cardiovascular Diabetology

ISSN: 1475-2840