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Table 1 Demographic and clinical parameters in the population according to the presence or absence of diabetes

From: The activity of circulating dipeptidyl peptidase-4 is associated with subclinical left ventricular dysfunction in patients with type 2 diabetes mellitus

Parameters Non-diabetic subjects Diabetic patients p value
(n = 59) (n = 83)
Age (years) 63.6 ± 9.5 65.4 ± 8.4 0.214
Male/female (n, %) 33/26, 56/44 52/31, 63/37 0.264
BMI (Kg/m2) 28 ± 4.3 29.8 ± 5 0.049
SBP (mmHg) 143 ± 22 139 ± 21.4 0.333
DBP (mmHg) 80 (72-90) 75 (70-80) 0.002
MBP (mmHg) 102 ± 13.9 96.5 ± 12.3 0.016
PP (mmHg) 62.3 ± 17.5 64 ± 19.4 0.605
HbA1c (%) 5.3 (5.1-5.4) 6.7 (5.9-7.5) <0.001
Fasting glucose (mg/dL) 92 (87-95) 115 (101-138) <0.001
Comorbidities, (n, %)    
Hypertension 41, 70 68, 82 0.064
Hypertriglyceridemia 8, 14 18, 22 0.158
Hypercholesterolemia 34, 58 23, 28 <0.001
Obesity 18, 30 39, 47 0.049
CKD 5, 8.5 15, 18 0.115
Treatment, (n, %)    
Antidiabetic agents    
Metformin 0, 0 25, 30  
Sulfonylureas 0, 0 18, 22  
Other oral anti-diabetic drugs 0, 0 22, 27  
Insulin 0, 0 23, 28  
Anti-hypertensive agents    
ACEi/ARAs 16, 28 49, 59 <0.001
Diuretics 6, 10 20, 24 0.030
Ca2 + -antagonists 10, 17 19, 23 0.274
Beta-blockers 5, 9 20, 24 0.014
Other pharmacological agents    
Statins 14, 24 48, 58 <0.001
Anti-coagulants 0, 0 14, 16  
Anti-aggregants 14, 24 44, 53 <0.001
  1. BMI means body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; MBP, mean blood pressure; PP, pulse pressure; HbA1c, glycosylated haemoglobin; CKD, chronic kidney disease; ACEi, angiotensin converting enzyme inhibitor; ARA, angiotensin II type 1 receptor antagonist. Obesity was defined as BMI ≥ 30 kg/m2 and CKD was diagnosed if the estimated glomerular filtration rate was < 60 ml/min/1.73m2 and/or microalbuminuria was present defined as an albumin-to-creatinine ratio between 30 and 300 mg/g. Values are expressed as mean ± SD or median (interquartile range), and categorical variables as numbers and percentages.