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Table 1 Baseline characteristics of the study population ( n= 708) according to urinary adiponectin tertile

From: Urinary adiponectin concentration is positively associated with micro- and macro-vascular complications

  Tetile-1 (n = 236) Tertile-2 (n = 236) Tertile-3 (n = 236) P value
  (<3.19 μg/gCr) (3.19-7.07 μg/gCr) (≥7.07 μg/gCr)  
Age (years) 53.69 ± 13.86*† 61.15 ± 11.65 63.02 ± 10.27 <0.001
Sex (Female/Male) 102/134 145/91 124/112 <0.001
Fasting plasma glucose (mmol/l) 7.03 ± 1.77† 7.47 ± 1.85‡ 8.13 ± 2.48 <0.001
HbA1C (%) 6.51 ± 1.11† 6.75 ± 1.22‡ 7.23 ± 1.54 <0.001
Total cholesterol (mmol/l) 4.88 ± 1.05 4.87 ± 0.89 4.95 ± 0.92 0.601
Triglycerides(mmol/l) 1.57 ± 1.04† 1.71 ± 1.02 1.82 ± 1.11 0.035
HDL-cholesterol (mmol/l) 1.31 ± 0.31 1.29 ± 0.31 1.33 ± 0.35 0.493
LDL-cholesterol (mmol/l) 2.82 ± 0.88 2.73 ± 0.77 2.76 ± 0.83 0.479
Fasting insulin (pmol/l) 60.73 ± 31.79 67.05 ± 32.25 66.99 ± 30.28 0.045
HOMA-IR 3.27 ± 1.97† 3.76 ± 2.28 4.11 ± 2.53 <0.001
hs CRP (mg/l) 0.22 ± 0.52 0.19 ± 0.43 0.23 ± 0.56 0.625
BMI (kg/m2) 24.76 ± 3.43 24.68 ± 3.40 24.93 ± 3.22 0.725
Waist circumference (cm) 85.28 ± 9.63 85.95 ± 8.77 87.11 ± 8.59 0.088
Systolic Blood Pressure (mmHg) 126.98 ± 15.04† 129.83 ± 15.36‡ 135.12 ± 16.86 <0.001
Diastolic Blood Pressure (mmHg) 80.56 ± 10.78† 81.70 ± 10.39‡ 84.87 ± 10.99 <0.001
eCcr (ml/min) 93.59 ± 26.32*† 86.67 ± 26.73 84.18 ± 27.32 0.001
Current alcohol intake (%) 22.0 15.7 21.6 0.156
Current smoker (%) 17.8 11.9 13.6 0.171
Taking ACEi/ARB medication (%) 14.8 19.9 19.9 0.249
Urinary A/C ratio (mg/g) 21.65 ± 34.80*† 30.48 ± 47.62 60.76 ± 64.85 <0.001
Serum adiponectin (μg/ml) 6.46 ± 5.06*† 8.36 ± 6.25 8.64 ± 6.61 0.001
  1. All data are expressed as mean ± SD or percentages. P value = the difference among the three groups using ANOVA test. *P value <0.05 Tertile-1 vs. Tertile-2. †P value <0.05 Tertile-1 vs. Tertile-3. ‡P value <0.05 Tertile-2 vs. Tertile-3. (Post-hoc analysis using Bonferroni method).
  2. SD standard deviation, HbA1C glycated hemoglobin, HDL high density lipoprotein, LDL low density lipoprotein, HOMA-IR Homeostasis model assessment of insulin resistance, hs CRP high sensitivity C-reactive protein, BMI body mass index, eCcr estimated creatinine clearance rate, ACEi ACE inhibitor, ARB Angiotensin receptor blocker, A/C ratio albumin/creatinine ratio.