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Table 6 Achieved HbA1c Level <7.0%, withdrawal at 1 year, and hypoglycemic episodes by duration of diabetes

From: Baseline and 1-year interim follow-up assessment of Japanese patients initiating insulin therapy who were enrolled in the cardiovascular risk evaluation in people with type 2 diabetes on insulin therapy study: an international, multicenter, observational study

  All <5 years ≥5, <10 years ≥10, <15 years ≥15 years P 1)
Achievement of HbA1c level <7.0% 193/482 (40.0%) 44/95 (46.3%) 49/120 (40.8%) 50/129 (38.8%) 47/132 (35.6%) N.S.
Withdrawal from insulin at 1 year 27/488 (5.5%) 9/95 (9.5%) 8/121 (6.6%) 7/129 (5.4%) 3/137 (2.2%) *
Patients with any hypoglycemic episodes 105/482 (21.8%) 19/95 (20.0%) 17/120 (14.2%) 39/127 (30.7%) 29/134 (21.6%) N.S.
Number of any hypoglycemic episodes/patient 1.44 ± 5.18 0.84 ± 2.72 1.06 ± 4.81 2.61 ± 7.87 1.11 ± 3.22 N.S.
Patients with severe hypoglycemic episodes 8/483 (1.7%) 2/95 (2.1%) 1/120 (0.8%) 2/128 (1.6%) 3/134 (2.2%) N.S.
Number of severe hypoglycemic episodes/patient 0.03 ± 0.35 0.03 ± 0.23 0.01 ± 0.09 0.02 ± 0.12 0.07 ± 0.62 N.S.
  1. 1)Trend test by Cochran-Armitage test for categorical variables and analysis of variance with contrast statement for numerical variables.
  2. N.S. not statistically significant, *P < .05.