| Baseline | 7 days post-MI | 28 days post-MI | ||||||
---|---|---|---|---|---|---|---|---|---|
 | SHAM | MI + PBS | MI + MSC | SHAM | MI + PBS | MI + MSC | SHAM | MI + PBS | MI + MSC |
HR (bpm) | 647 ± 16 | 662 ± 16 | 689 ± 9* | 720 ± 8 | 699 ± 10 | 713 ± 12 | 710 ± 11 | 720 ± 13 | 731 ± 6 |
FS (%) | 49.58 ± 0.75 | 48.88 ± 1.02 | 48.74 ± 0.46 | 49.12 ± 0.78 | 29.88 ± 3.16* | 30.90 ± 2.03* | 48.99 ± 0.70 | 27.34 ± 2.84* | 32.90 ± 2.02* |
EF (%) | 82.07 ± 0.72 | 81.37 ± 1.01 | 81.23 ± 0.45 | 81.80 ± 0.76 | 56.51 ± 4.88* | 58.48 ± 2.9* | 81.48 ± 0.74 | 52.80 ± 2.93* | 61.10 ± 2.88*†|
IVSd (mm) | 0.77 ± 0.02 | 0.81 ± 0.02 | 0.79 ± 0.01 | 0.76 ± 0.02 | 0.73 ± 0.04 | 0.84 ± 0.01*†| 0.79 ± 0.01 | 0.76 ± 0.03 | 0.85 ± 0.01*†|
LVIDd (mm) | 3.19 ± 0.07 | 3.21 ± 0.08 | 3.28 ± 0.04 | 3.02 ± 0.04 | 4.31 ± 0.24* | 4.01 ± 0.13* | 3.23 ± 0.08 | 4.32 ± 0.21* | 4.27 ± 0.13* |
LVPWd (mm) | 0.72 ± 0.01 | 0.69 ± 0.02 | 0.80 ± 0.02†| 0.74 ± 0.02 | 0.68 ± 0.07 | 0.86 ± 0.03*†| 0.77 ± 0.02 | 0.71 ± 0.04 | 0.91 ± 0.03 |
IVSs (mm) | 0.91 ± 0.02 | 0.91 ± 0.02 | 0.90 ± 0.01 | 0.88 ± 0.02 | 0.87 ± 0.05 | 0.92 ± 0.02 | 0.88 ± 0.01 | 0.84 ± 0.02 | 0.96 ± 0.01*†|
LVIDs (mm) | 1.61 ± 0.04 | 1.65 ± 0.06 | 1.68 ± 0.03 | 1.54 ± 0.04 | 3.06 ± 0.28* | 2.79 ± 0.16* | 1.65 ± 0.06 | 3.17 ± 0.26* | 2.89 ± 0.17* |
LVPWs (mm) | 0.97 ± 0.02 | 0.98 ± 0.04 | 1.04 ± 0.01 | 0.88 ± 0.02 | 0.83 ± 0.09 | 1.01 ± 0.02*†| 0.96 ± 0.02 | 0.82 ± 0.06* | 1.11 ± 0.03*†|