|
Variables
|
CFR ≥ 2.5, n = 82
|
CFR < 2.5, n = 29
|
p
|
|---|
|
Age (years)
|
62 ± 9
|
67 ± 9
|
0.02
|
|
Male
|
43 (52.0)
|
17 (59.0)
|
0.57
|
|
BMI (kg/m2)
|
24.5 ± 3.7
|
23.3 ± 3.1
|
0.11
|
|
FBS (mmol/l)
|
8.6 ± 2.6
|
8.4 ± 2.2
|
0.79
|
|
HbA1c (%) [NGSP]
|
7.7 ± 1.2
|
7.7 ± 1.0
|
0.90
|
|
eGFR (ml/min./1.73 m2)
|
80.6 ± 16.9
|
77.2 ± 19.3
|
0.39
|
|
Hypertension
|
48 (59.3)
|
19 (63.3)
|
0.51
|
|
Dyslipidemia
|
43 (53.1)
|
15 (50.0)
|
0.95
|
|
Smoking
|
15 (18.5)
|
6 (20.0)
|
0.78
|
|
Diabetes treatment
| | | |
|
Sulfonylurea
|
45 (55.6)
|
15 (50.0)
|
0.77
|
|
Biguanide
|
16 (19.8)
|
8 (26.7)
|
0.36
|
|
Thiazolidinedione
|
24 (29.6)
|
5 (16.7)
|
0.21
|
|
alpha-glucosidase inhibitor
|
36 (44.4)
|
7 (23.3)
|
0.06
|
|
Insulin
|
13 (16.0)
|
6 (20.0)
|
0.55
|
|
Other treatment
| | | |
|
Statin
|
21 (25.9)
|
9 (30.0)
|
0.57
|
|
antihypertensive agents
|
38 (46.3)
|
13 (44.8)
|
0.89
|
|
EF (%)
|
67.7 ± 6.2
|
66.3 ± 6.1
|
0.56
|
|
LVMI (g/m2)
|
98.9 ± 23.3
|
88.9 ± 27.2
|
0.32
|
|
MDV baseline (cm/sec)
|
20 ± 5
|
22 ± 5
|
0.08
|
|
MDV hyperemia (cm/sec)
|
62 ± 14
|
52 ± 13
|
0.002
|
|
CFR
|
3.09 ± 0.38
|
2.33 ± 0.13
|
<0.001
|
- Data are presented as number (%) or mean ± SD.
- Abbreviations: BMI body mass index, FBS fasting blood sugar,HbA1c glycated hemoglobin, eGFR estimated glomerular filtration rate, EF ejection fraction, LVMI left ventricular mass index, SD standard deviation.
