Circulating concentrations of GLP-1 are associated with coronary atherosclerosis in humans

Table 1 Values are presented as n or median (interquartile range)

Characteristics	n = 303
Age (yrs)	63 (55–70)
Sex
Male	202
Female	101
Body mass index (kg/m ² )	26.2 (24.1-29.0)
Hypertension ^*
Yes	147
No	126
Diabetes mellitus ^*
Yes	20
No	253
Smoker ^†
Yes	42
No	230
Family history of CAD ^†
Yes	77
No	195
Laboratory profile
LDL-cholesterol (mg/dl)	122 (95–149)
HDL-cholesterol (mg/dl)	52 (44–59)
Triglycerides (mg/dl)	143 (106–207)
High-sensitivity CRP (mg/dl)	0.23 (0.05-0.54)
TNFa (pg/ml)	6,3 (4.5-7.9)
eGFR (ml/min)	71 (63–80)
IL6 (pg/ml)	0 (0–3.2)
GLP-1 (pM)	2.9 (1.5-4.9)
Medical treatment ^‡
Statin	120
Aspirin, Plavix or Marcumar	170
Betablocker	173
ACE-I or ARB	138
Diuretics	87
Insulin or OAD	16
CT data
Pericardial adipose tissue volume (ml) ^§	190 (132–259)
Number of coronary artery plaques (total) ^\|\|	3 (1–6) (range 0–26)
Number of calcified plaques	1 (0–3) (range 0–22)
Number of mixed plaques	0 (0–1) (range 0–10)

^*History of diabetes and hypertension is known in 273 patients.
^†History of smoking and family history of CAD is known in 272 patients.
^‡Medication is known in 258 patients.
^§Adequate image quality for evaluation of PAT volume was obtained in 287 patients.
^||Adequate image quality for evaluation of coronary plaques was obtained in 281 patients.

ISSN: 1475-2840