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Table 2 Local thermal hyperaemia, SNP- and PCH-induced vasodilation in healthy controls and patients with type 1 diabetes

From: Impaired skin microcirculation in paediatric patients with type 1 diabetes mellitus

 

Controls

Patients

p

ARR (cut-off: 4.3 [raPU*min])

   

  Median (range)

9.05 (0.40-64.9)

7.22 (0.62-27.6)

0.003

  Below cut-off

10/102

18/68 (26.5%)

 

AUCheat(cut-off:153 [raPU*min])

   

  Median (range)

399 (45–1053)

301 (0–988)

0.006

  Below cut-off

10/102

16/68 (23.5%)

 

maxSkBFheat(cut-off:5.9 [raPU])

   

  Median (range)

15.4 (1–40)

10.8 (1–36)

0.007

  bBelow cut-off

10/102

12/68 (17.6%)

 

AUCSNP (cut-off:18.6 [raPU*min])

   

  Median (range)

64.6 (0–244)

41.7 (0–215)

<0.001

  Below cut-off

10/102

17/68 (25%)

 

maxSkBFSNF (cut-off:3.0 [raPU])

   

  Median (range)

12.1 (1–47.8)

7.4 (1–30.9)

<0.001

  Below cut-off

10/102

14/68 (20.6%)

 

AUCPCH (cut-off:6.6 [raPU*min])

   

  Median (range)

30.6 (0.158)

27.9 (0–175)

0.427

  Below cut-off

10/102

8/68 (11.8%)

 

maxSkBFPCH (cut-off:2.1 [raPU])

   

  Median (range)

8.0 (1–45.6)

7.0 (1–35.4)

0.100

  Below cut-off

10/102

10/68 (14.7&)

 
  1. Per parameter, median and range as well as the number of individuals with an inadequately low response to exogenous stimulation of skin microcirculation are given.