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Table 2 Local thermal hyperaemia, SNP- and PCH-induced vasodilation in healthy controls and patients with type 1 diabetes

From: Impaired skin microcirculation in paediatric patients with type 1 diabetes mellitus

  Controls Patients p
ARR (cut-off: 4.3 [raPU*min])    
  Median (range) 9.05 (0.40-64.9) 7.22 (0.62-27.6) 0.003
  Below cut-off 10/102 18/68 (26.5%)  
AUCheat(cut-off:153 [raPU*min])    
  Median (range) 399 (45–1053) 301 (0–988) 0.006
  Below cut-off 10/102 16/68 (23.5%)  
maxSkBFheat(cut-off:5.9 [raPU])    
  Median (range) 15.4 (1–40) 10.8 (1–36) 0.007
  bBelow cut-off 10/102 12/68 (17.6%)  
AUCSNP (cut-off:18.6 [raPU*min])    
  Median (range) 64.6 (0–244) 41.7 (0–215) <0.001
  Below cut-off 10/102 17/68 (25%)  
maxSkBFSNF (cut-off:3.0 [raPU])    
  Median (range) 12.1 (1–47.8) 7.4 (1–30.9) <0.001
  Below cut-off 10/102 14/68 (20.6%)  
AUCPCH (cut-off:6.6 [raPU*min])    
  Median (range) 30.6 (0.158) 27.9 (0–175) 0.427
  Below cut-off 10/102 8/68 (11.8%)  
maxSkBFPCH (cut-off:2.1 [raPU])    
  Median (range) 8.0 (1–45.6) 7.0 (1–35.4) 0.100
  Below cut-off 10/102 10/68 (14.7&)  
  1. Per parameter, median and range as well as the number of individuals with an inadequately low response to exogenous stimulation of skin microcirculation are given.