Skip to main content

Table 1 Body weight, heart weight and hemodynamic parameters of sham, streptozotocin-treated (STZ), myocardial infarcted (MI) and streptozotocin-treated myocardial infarcted (MI + STZ) rats

From: The neurogenic response of cardiac resident nestin(+) cells was associated with GAP43 upregulation and abrogated in a setting of type I diabetes

  Body weight (grams) Heart weight (grams) MAP (mmHg) LVSP (mmHg) LV + dP/dt (mmHg/sec) LV-dP/dt (mmHg/sec) Scar weight (grams) Scar area (cm2) Plasma glucose (mM)
sham (n = 8) 350 ± 19 1.13 ± 0.05 126 ± 4 147 ± 5 6859 ± 2241 5832 ± 258 - - 7 ± 1
STZ (n = 7) 315 ± 6 1.08 ± 0.06 88 ± 3* 112 ± 5* 6106 ± 322* 4144 ± 323* - - 33 ± 1*
MI (n = 7-8) 335 ± 8 1.14 ± 0.08 108 ± 3* 134 ± 5 5762 ± 172* 4392 ± 280* 0.055 ± 0.008 0.678 ± 0.11 8 ± 2
MI + STZ (n = 8-12) 266 ± 8*** 0.932 ± 0.05*** 81 ± 3** 97 ± 2*** 4658 ± 115*** 2935 ± 103*** 0.058 ± 0.004 0.754 ± 0.06 29 ± 1*
  1. MI indicates myocardial infarction; MAP, mean arterial pressure; LVSP, left ventricular systolic pressure; LV + dP/dt, rate of left ventricular contraction; LV -dP/dt, rate of left ventricular relaxation. Data are presented as mean ± S.E.M, evaluated by a Student’s unpaired t-test or a Newman-Keuls Multiple Comparisons post-hoc test, (*) represents P < 0.05 versus sham, (**) represents P < 0.05 versus sham and MI, (***) versus sham, MI and STZ and (n) number of rats examined.