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Table 1 Body weight, heart weight and hemodynamic parameters of sham, streptozotocin-treated (STZ), myocardial infarcted (MI) and streptozotocin-treated myocardial infarcted (MI + STZ) rats

From: The neurogenic response of cardiac resident nestin(+) cells was associated with GAP43 upregulation and abrogated in a setting of type I diabetes

 

Body weight (grams)

Heart weight (grams)

MAP (mmHg)

LVSP (mmHg)

LV + dP/dt (mmHg/sec)

LV-dP/dt (mmHg/sec)

Scar weight (grams)

Scar area (cm2)

Plasma glucose (mM)

sham (n = 8)

350 ± 19

1.13 ± 0.05

126 ± 4

147 ± 5

6859 ± 2241

5832 ± 258

-

-

7 ± 1

STZ (n = 7)

315 ± 6

1.08 ± 0.06

88 ± 3*

112 ± 5*

6106 ± 322*

4144 ± 323*

-

-

33 ± 1*

MI (n = 7-8)

335 ± 8

1.14 ± 0.08

108 ± 3*

134 ± 5

5762 ± 172*

4392 ± 280*

0.055 ± 0.008

0.678 ± 0.11

8 ± 2

MI + STZ (n = 8-12)

266 ± 8***

0.932 ± 0.05***

81 ± 3**

97 ± 2***

4658 ± 115***

2935 ± 103***

0.058 ± 0.004

0.754 ± 0.06

29 ± 1*

  1. MI indicates myocardial infarction; MAP, mean arterial pressure; LVSP, left ventricular systolic pressure; LV + dP/dt, rate of left ventricular contraction; LV -dP/dt, rate of left ventricular relaxation. Data are presented as mean ± S.E.M, evaluated by a Student’s unpaired t-test or a Newman-Keuls Multiple Comparisons post-hoc test, (*) represents P < 0.05 versus sham, (**) represents P < 0.05 versus sham and MI, (***) versus sham, MI and STZ and (n) number of rats examined.
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Cardiovascular Diabetology

ISSN: 1475-2840