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Table 2 Univariate associations between plasma fibulin-1 concentrations and clinical variables in 90 patients with type 2 diabetes and 90 gender- and age-matched controls

From: Plasma levels of the arterial wall protein fibulin-1 are associated with carotid-femoral pulse wave velocity: a cross-sectional study

 

Type 2 diabetes patients

Controls

(n = 90)

(n = 90)

 

β ± SE pr μg/mL plasma fibulin-1

P-value

β ± SE pr μg/mL plasma fibulin-1

P-value

Age (years)

0.5 ± 0.3

0.10

0.12 ± 0.32

0.71

HbA1c (%)

−3.8 ± 4.7

0.42

9.3 ± 9.3

0.32

Body Mass Index (kg/m2)

−1.1 ± 0.6

0.10

−0.01 ± 0.81

0.99

Plasma total cholesterol (mmol/l)

0.59 ± 3.84

0.88

2.33 ± 3.10

0.45

Plasma creatinine (μmol/liter)

0.24 ± 0.21

0.25

−0.41 ± 0.22

0.07

Estimated glomerular filtration rate (mL/min/1.73 m2)

−0.40 ± 0.19

<0.05

−0.11 ± 0.25

0.65

Ln-transformed Urine albumine/creatinine ratio (mg/mmol)

1.83 ± 3.10

0.55

4.26 ± 3.8

0.27

Office systolic BP (mmHg)

−0.06 ± 0.18

0.74

−0.14 ± 0.18

0.43

Office diastolic BP (mmHg)

−0.33 ± 0.35

0.36

−0.34 ± 0.32

0.28

Office pulse pressure (mmHg)

0.04 ± 0.23

0.86

−0.07 ± 0.26

0.80

Office heart rate (beats/min)

0.01 ± 0.20

0.98

−0.15 ± 0.34

0.66

24-h ABPM systolic BP (mmHg)

−0.31 ± 0.28

0.26

−0.13 ± 0.28

0.63

24-h ABPM diastolic BP (mmHg)

−0.78 ± 0.40

0.053

−0.24 ± 0.43

0.58

24-h ABPM pulse pressure (mmHg)

0.08 ± 0.36

0.82

−0.07 ± 0.38

0.86

24-h ABPM heart rate (beats/min)

0.22 ± 0.32

0.70

−0.40 ± 0.34

0.25

  1. SE Standard Error, BP Blood Pressure, ABPM Ambulatory Blood Pressure Monitoring.