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Table 1 Patient characteristics

From: Plasma levels of the arterial wall protein fibulin-1 are associated with carotid-femoral pulse wave velocity: a cross-sectional study

 

Diabetics

Controls

P-value

Sex (male/female)

46/44

46/44

-

Age (years)

59 ± 10

59 ± 10

-

Diabetes duration (years) (median(IQR))

1.9(0.8;3.2)

-

-

HbA1c (%) (median(IQR))

6.5 (6.2;6.8)

5.7 (5.5;5.8)

<0.001

Body Mass Index (BMI)(kg/m2)

30 ± 5

26 ± 4

<0.001

Smoking (present/previous/never)

19/33/38

19/30/41

0.88

Statins (yes/no)

70/20

16/74

<0.001

Antihypertensive treatment (yes/no)

57/33

25/65

<0.001

History of cardiovascular disease (yes/no)

17/73

10/80

<0.001

Total-cholesterol (mmol/l)

4.3 ± 0.8

5.7 ± 1.0

<0.001

LDL-cholesterol (mmol/l)

2.2 ± 0.7

3.4 ± 1.0

<0.001

HDL-cholesterol (mmol/l)

1.4 ± 0.3

1.7 ± 0.6

<0.001

Triglycerides (mmol/l) (median(IQR))

1.4 (1.1;2.0)

1.2 (0.9;1.6)

<0.05

Office systolic BP (mmHg)

126 ± 12

132 ± 14

<0.01

Office diastolic BP (mmHg)

79 ± 8

84 ± 10

<0.001

Office pulse pressure (mmHg)

47 ± 10

48 ± 10

0.73

Office mean arterial pressure (mmHg)

95 ± 8.3

100 ± 11

<0.01

Office heart rate (beats/min)

66 ± 10

62 ± 10

<0.01

24-h ABPM systolic BP (mmHg)

126 ± 11

125 ± 12

0.40

24-h ABPM diastolic BP (mmHg)

75 ± 8

76 ± 8

0.26

24-h ABPM pulse pressure (mmHg)

52 ± 9

49 ± 9

<0.05

24-h ABPM mean arterial pressure (mmHg)

92 ± 8

93 ± 8

0.86

24-h heart rate (beats/min)

74 ± 10

68 ± 9

<0.01

Creatinine (μmol/liter)

72 ± 14

76 ± 14

<0.01

Estimated GFR (mL/min/1.73 m2) (median(IQR))

75 (66;87)

70(63;78)

<0.01

Urine albumine/creatinine ratio (mg/mmol) (median(IQR))

0.40 (0.28;0.98)

0.25 (0.17;0.40)

<0.001

Carotid-femoral pulse wave velocity (m/s)

9.3 ± 2

8.0 ± 1.6

<0.001

  1. IQR Inter Quartile Range, LDL Low Density Lipoprotein, HDL High Density Lipoprotein, BP Blood Pressure, ABPM Ambulatory Blood Pressure Monitoring, GFR Glomerular Filtration Rate. History of cardiovascular disease: Previous acute myocardial infarction, percutaneous cardiac intervention, coronary bypass or stroke.