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Table 4 Systolic and diastolic blood pressure adjusted-means* among men and women according to genotype [mean ± SD, (95 % CI)]

From: Effects of FTO RS9939906 and MC4R RS17782313 on obesity, type 2 diabetes mellitus and blood pressure in patients with hypertension

 

Men

Women

rs9939609

TT

TA/AA

P value

TT

TA/AA

P value

(n = 30)

(n = 56)

(n = 45)

(n = 86)

Systolic BP (mmHg)

153.7 ±20.7

150.8 ±20.9

0.6

155.9 ±21.5

150.8 ±20.4

0.2

(146.1 – 161.3)

(145.3 – 156.4)

(149.6 – 162.2)

(146.4 – 155.3)

Diastolic BP (mmHg)

89.9 ±12.5

87.7 ±12.7

0.5

87.5 ±12.7

87.2 ±12.1

0.9

(85.4 – 94.4)

(84.5 – 91.0)

(83.7 – 91.2)

(84.6 – 89.9)

Mean BP (mmHg)

111.1 ±13.7

108.8 ±13.5

0.5

110.6 ±13.7

108,2 ±13.7

0.5

(106.2-116.0)

(105.2-112.3)

(106.5-114.7)

(105,3-111,2)

rs17782313

TT

TC/CC

P value

TT

TC/CC

P value

(n = 66)

(n = 20)

(n = 80)

(n = 51)

Systolic BP (mmHg)

154.2 ±20.3

144.2 ±20.1

0.05

154.1 ±20.6

150.2 ±20.7

0.3

(149.2 – 159.1)

(135.3 – 153.2)

(149.5 – 158.6)

(144.3 – 155.9)

Diastolic BP (mm Hg)

90.1 ±12.2

83.2 ±12.1

0.03

87.5 ±12.5

86.9 ±12.9

0.8

(87.2 – 92.9)

(77.9 – 88.5)

(84.8 – 90.2)

(83.5 – 90.5)

Mean BP (mmHg)

111.3 ±13.5 (108.1-114.6)

103.9 ±13.4 (98.0-109.8)

0.02

109.8 ±13.4 (106.8-112.7)

107.9 ±13.5 (104.1-111.7)

0.5

  1. * Means adjusted for age and BMI.