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Table 3 Characteristic of men and women according to polymorphism risk allele C for MC4R rs17782313 [mean ± SD, n (%)]

From: Effects of FTO RS9939906 and MC4R RS17782313 on obesity, type 2 diabetes mellitus and blood pressure in patients with hypertension

 

Men

Women

 

TT

TC/CC

P value

TT

TC/CC

P value

 

(n = 66)

(n = 20)

(n = 80)

(n = 51)

Age (years)

61.1 ±10.3

59.2 ±11.3

0.5

59.7 ±12.1

59.2 ±10.8

0.8

Body mass index (kg/m2)

28.9 ±4.4

30.1 ±4.1

0.3

30.1 ±5.4

31.5 ±5.7

0.2

Waist circumference (cm)

102.5 ±11.1

105.1 ±11.9

0.4

98.5 ±11.1

102.3 ±12.2

0.07

Neck circumference (cm)

41.3 ±2.9

41.2 ±2.7

0.9

36.1 ±2.8

37.4 ±2.9

0.01

Body Adiposity Index (%)

29.4 ±3.4

29.4 ±3.5

0.9

37.6 ±6.0

38.1 ±5.9

0.7

LAP* (cm.mmol.l)

4.2 ±0.7

4.3 ±0.8

0.9

4.0 ±0.6

4.2 ±0.7

0.07

SBP§ (mmHg)

154.3 ±21.2

143.8 ±18.1

0.04

154.3 ±22.4

149.7 ±17.9

0.2

DBP¶ (mmHg)

89.8 ±12.8

84.1 ±11.7

0.08

87.5 ±13.9

86.9 ±12.8

0.8

Type-2 Diabetes

  

0.9

  

0.02

 Yes

30 (76.9)

9 (23.1)

 

29 (50.0)

29 (50.0)

 

 No

36 (76.6)

11 (23.4)

 

51 (69.9)

22 (30.1)

 
  1. * LAP Lipid Accumulation Product, log-transformed; § systolic blood pressure; ¶ diastolic blood pressure.