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Table 1 Characteristic of participants according to polymorphism [mean ± SD, n (%)]

From: Effects of FTO RS9939906 and MC4R RS17782313 on obesity, type 2 diabetes mellitus and blood pressure in patients with hypertension

 

rs9939609

rs17782313

TT

TA/AA

P value

TT

TC/CC

P value

(n = 75)

(n = 142)

(n = 146)

(n = 71)

Age (years)

59.6 ±11.4

60.2 ±11.1

0.7

60.3 ±11.3

59.2 ±10.8

0.5

Sex

  

0.9

  

0.02

 Men

30 (34.9)

56 (65.1)

 

66 (76.7)

20 (23.3)

 

 Women

45 (34.4)

86 (65.4)

 

80 (61.1)

51 (38.9)

 

Vigorous physical activity

  

0.7

  

0.2

 Yes

11 (31.4)

24 (68.6)

 

27 (77.1)

8 (22.9)

 

 No

64 (35.4)

117 (64.6)

 

118 (65.2)

63 (34.8)

 

Body mass index (kg/m2)

28.9 ±4.6

30.7 ±5.2

0.02

29.6 ±4.8

31.1 ±5.4

0.04

Waist circumference (cm)

99.5 ±11.5

102.1 ±11.6

0.1

100.3 ±11.2

103.1 ±12.1

0.1

Neck circumference (cm)

37.7 ±3.4

38.9 ±3.8

0.03

38.5 ±3.8

38.5 ±3.3

0.9

Body Adiposity Index (%)

33.6 ±5.8

34.9 ±6.9

0.2

33.9 ±6.5

35.7 ±6.6

0.07

LAP* (cm.mmol.l)

4.1 ±0.8

4.2 ±0.6

0.4

4.1 ±0.6

4.2 ±0.7

0.2

Type-2 Diabetes

  

0.7

  

0.07

 Yes

32 (33.0)

65 (67.0)

 

59 (60.8)

38 (39.2)

 

 No

43 (35.8)

77 (64.2)

 

87 (72.5)

33 (27.5)

 

SBP§ (mmHg)

155.2 ±22.7

150.8 ±19.7

0.1

154.3 ±21.8

147.9 ±18.1

0.04

DBP¶ (mmHg)

88.9 ±13.2

87.1 ±13.1

0.3

88.5 ±13.4

86.1 ±12.4

0.2

Mean blood pressure (mmHg)

111.0 ±14.1

108.3 ±13.1

0.2

110.5 ±13.9

106.7 ±12.3

0.06

  1. *LAP Lipid Accumulation Product, log-transformed; § systolic blood pressure; ¶ diastolic blood pressure.