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Figure 7 | Cardiovascular Diabetology

Figure 7

From: Exercise and diabetes have opposite effects on the assembly and O-GlcNAc modification of the mSin3A/HDAC1/2 complex in the heart

Figure 7

Effects of diabetes and 4 weeks of exercise on the association of mSin3A/HDAC1/2 complex with OGT in type 2 diabetic db/db and non-diabetic C57BL/6J hearts. (A) Immunoblot and (B-E) blot quantification showing the association of OGT with the mSin3A/REST/HDAC1/2 complex in C57BL/6J (C57) and db/db (db) mice who were treadmill exercise trained (Ex) or sedentary (Sed) for 4 weeks. N = 3 per group. * Significant effect of genotype within exercise group, P < 0.05.

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